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Database: UniProt
Entry: W5L787_ASTMX
LinkDB: W5L787_ASTMX
Original site: W5L787_ASTMX 
ID   W5L787_ASTMX            Unreviewed;      1125 AA.
AC   W5L787;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   25-OCT-2017, entry version 29.
DE   SubName: Full=Potassium voltage-gated channel, subfamily H (eag-related), member 3 {ECO:0000313|Ensembl:ENSAMXP00000015699};
OS   Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Characidae; Characidae incertae sedis; Astyanax clade;
OC   Astyanax.
OX   NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000015699, ECO:0000313|Proteomes:UP000018467};
RN   [1] {ECO:0000313|Ensembl:ENSAMXP00000015699, ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=female {ECO:0000313|Ensembl:ENSAMXP00000015699};
RA   Jeffery W., Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAMXP00000015699}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSAMXP00000015699}.
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DR   EMBL; APWO01119421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01119422; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01119423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01119424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01119425; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01119426; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01119427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSAMXT00000015699; ENSAMXP00000015699; ENSAMXG00000015182.
DR   GeneTree; ENSGT00900000140833; -.
DR   OMA; YINYASH; -.
DR   OrthoDB; EOG091G0OXR; -.
DR   Proteomes; UP000018467; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043855; F:cyclic nucleotide-gated ion channel activity; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR   CDD; cd00038; CAP_ED; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018467};
KW   Ion channel {ECO:0000256|SAAS:SAAS00904115};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00502630, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00903208};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00904256};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00903350};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00903851}.
FT   TRANSMEM    286    314       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    335    361       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    495    519       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       16     64       PAS. {ECO:0000259|PROSITE:PS50112}.
FT   DOMAIN      597    714       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   COILED      857    884       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1125 AA;  123599 MW;  AEA38B72A4EBC35A CRC64;
     SNFVLGNAQV QSLYPIVYCS DGFCELTGYA RAELMQKSCA CHFLYGPETS DRLTTQIQSA
     LDERREFKTE LVFYKKGGER HWLCLVLIAK VKKDKNKAVI ALMSSKEAKN RKNEQLFNQG
     LNSNEETGLE VHKVTRPQGF NANRRRSRAV LYQLSGHLQK QDKSKLKINN NMFGEKPPIP
     EYKVAAIQKS RFILLHYGTF KAGWDWLILL ATFYVAVTVP YNVCFTVVGG RDDGSTPRSP
     PSVSDILVEI LFILDILLNF RTTFVSTSGQ VVYDARSICV HYVTTWLFVD LIAALPFDLL
     YAFNVSVYFG VHLLKTVRLL RLLRLLQKLE RYSQYSAVVL TLLMSMFALL AHWMACVWYF
     IGRREIENNS PGSWDIGWLH ELAKRLGTPY FLSPLTALLP DSLQASFLDG LSVNSTQWNS
     SSAEAAVQET AVNSSQWNAT GVGPAGGVST GQAGSVLGGG PSVRSSYVTS LYFALSSLTS
     VGFGNVSANT DTEKIFSICT MLIGALMHAV VFGNVTAIIQ RMYSRRSLYH TRTKDLKDFI
     RVHRLPKALE QRMLECFQTT WSVNNGIDVS ELLKDFPDEL RADIAMHLNK ELLQLPLFES
     ASRGCLRSLS LIIKTSFCAP GEFLIRQGDA LQAIYFVCSG SMEVLKDNTV LAILGKGDLI
     GSDSLTREQV IKTNANVKAL TYCDLQYISL KGLREVLRLY PEYAQKFVSE IQHDLTYNLR
     EGNGADVDWE SNGGLVKKLP SIREDEENDE EQHTVSRAPR SPLRLTRGLN SPLRSPLLPP
     RPFRPPSDHN RPATLQIPVV SFSSAPPELS PRFVDGIETE SNSGSAQRFE FSSNLPHSGP
     PSPIPVSPEQ VETRQSINKL SEEMTSLSQQ VSQLSKELQE MSRLLRPLFL TTSQPLLTTL
     PLSMTPPPSS TSGPSIASPV APPPHHLAPT CSPLRPPCSL LDSSDLGGIA GLSSCLIPTS
     PQKPQAQPQA PLGVNSKGPP HASLSPTDTV QPNSPLSPSN GQQAPDRPPL ASRTPSPSLS
     FSLSLSSSRS QSPSFSPCQG PHPSRPSLAP PNSQEVPLSL QKSHCSAPAS LSSSPGGPLW
     FQQTSSPVSS PVPPQLELEM QEWDAQGGLS SAEQISFIDE EGPPL
//
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