GenomeNet

Database: UniProt
Entry: W5LIJ4_ASTMX
LinkDB: W5LIJ4_ASTMX
Original site: W5LIJ4_ASTMX 
ID   W5LIJ4_ASTMX            Unreviewed;       860 AA.
AC   W5LIJ4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   25-OCT-2017, entry version 25.
DE   SubName: Full=Transient receptor potential cation channel, subfamily C, member 7a {ECO:0000313|Ensembl:ENSAMXP00000019656};
OS   Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Characidae; Characidae incertae sedis; Astyanax clade;
OC   Astyanax.
OX   NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000019656, ECO:0000313|Proteomes:UP000018467};
RN   [1] {ECO:0000313|Ensembl:ENSAMXP00000019656, ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=female {ECO:0000313|Ensembl:ENSAMXP00000019656};
RA   Jeffery W., Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSAMXP00000019656}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSAMXP00000019656}.
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DR   EMBL; APWO01038111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01038112; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01038113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01038114; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01038115; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APWO01038116; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSAMXT00000019656; ENSAMXP00000019656; ENSAMXG00000018973.
DR   GeneTree; ENSGT00760000119180; -.
DR   OMA; IMKWVLX; -.
DR   OrthoDB; EOG091G01FB; -.
DR   Proteomes; UP000018467; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005463; TRPC7_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   PANTHER; PTHR10117:SF9; PTHR10117:SF9; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00933366};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018467};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    341    361       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    373    393       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    462    483       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    568    591       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    611    627       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    639    661       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       39     88       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   COILED      818    849       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   860 AA;  98567 MW;  71F7F807DD4AB830 CRC64;
     EAMQRRHTTL REKGRRGPAY MFSERGTSLT AEEERFLDAA EYGNIPVVRK MLEESKTLNV
     NCMDYMGQNA LQLAVGNEHL EVTELLLKTE GLARIGDALL LAISKGYVRI VEAILAHPAF
     EGGLRFAHSP LEQEPREDDF YAYDEDGTRF SQDVTPVILA AHCQEYEIVH ILLLKGARIE
     KPHDHFCKCS ECMESQKQDS FSHSRSRMNA YKGLASAAYL SLSSEDPVLT ALELSNELSQ
     LANIETEFKN DYRKLSMQCK DFVVGVLDLC RNTEEVEAIL NGDVDHNTPS EHNRPCLSRV
     KLAIKYEVKK FVAHPNCQQQ LLTLWYENLS GLRQQPIGVK CLTVLGVMVG LPFLAIAYWI
     MPYSKVGQVL RSPFMKFVAH AVSFTTFLGL LVLNASDRFL GVKNLPNETI TDHPRQVFRV
     KTTQFSWTEM LIMKWVLGMI WSECKEIWED GPREYIMHLW NILDFGMLSI FIASYTARLM
     AFLRASNAQL YVDLYVTTSD LSNATLPEEV AYFTYARNRW LPSDPQLISE GLYSIAVVLS
     FSRIAYILPA NESFGPLQIS LGRTVKDIFK FMVIFIMVFL AFMIGMFNLY SYYLGAKYNP
     AFTTVEESFK TLFWSIFGLS EVISVVLKYD HKFIENIGYV LYGVYNVTMV IVLLNMLIAM
     INHSYQEIEE DADVEWKFAR AKLWLSYFDE GRTLPPPFNL VPSPKSFYYM ALRTRACLVR
     LCKARGRRHG SQRDMDIPGS RTKVRIWRTS VTKIRNCSTE EEQSKHSKRK DIPDKKSDVS
     SGNYDIPSKS NQVICKRFSK RFLQQVLAQS SFTETCELKE IKQDISSLRY ELLEEKSQAT
     EELADLIQQL GDRLSKSTKK
//
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