ID W5LY59_LEPOC Unreviewed; 1310 AA.
AC W5LY59;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Growth factor receptor bound protein 10 {ECO:0000313|Ensembl:ENSLOCP00000001066.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000001066.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000001066.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01012336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSLOCT00000001070.1; ENSLOCP00000001066.1; ENSLOCG00000000944.1.
DR GeneTree; ENSGT00530000063608; -.
DR HOGENOM; CLU_006259_0_0_1; -.
DR Proteomes; UP000018468; Linkage group LG11.
DR Bgee; ENSLOCG00000000944; Expressed in heart and 13 other cell types or tissues.
DR GO; GO:0003785; F:actin monomer binding; IEA:InterPro.
DR CDD; cd21799; WH2_Wa_Cobl; 1.
DR InterPro; IPR039895; COBL-like.
DR InterPro; IPR019025; Cordon-bleu_ubiquitin_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR47008; PROTEIN CORDON-BLEU; 1.
DR PANTHER; PTHR47008:SF1; PROTEIN CORDON-BLEU; 1.
DR Pfam; PF09469; Cobl; 1.
DR Pfam; PF02205; WH2; 2.
DR SMART; SM00246; WH2; 3.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS51082; WH2; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 1163..1183
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1203..1223
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT DOMAIN 1286..1306
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 12..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1051..1071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1215..1285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..390
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 748..782
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..883
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1051..1067
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1268
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1310 AA; 144856 MW; 0E5CBF59929B074C CRC64;
FAHITPAFVT LSRKMKARAP PPPQAPQPAP RRIFNTAKPT SLETTGPPAG EAKENVLHYA
VDLLVTLPQG FQTRTTVSGS KALMDLLVDL CSQYHLNPVY HTLELLSSDA QPVPFKPNTL
LGTLDVDKVL IKEKVIEEKV RRPPPKVPEK TVRLVVNYHR TQKAVVRVNP LVPLETLISV
ICEKCEFDPR HVILLKDNTS SKELDLSQSI SDLGIRELYV LDQSREPTRS SSLSNSASER
KSLLGFIKFN RRKTKTEDQR LADLDSTDDK NIQNCEIDHG GFILKVSSTA PNTPSVNVRP
SRLGQSQSVS NISRMSPRPE LKKRRAPRPP QLLPDLENLK KLASSSSQTP SQQKKRKAPA
PPATLALSTK TGDSAPVNHK AEEVDDNRQS TMGARRQVPL KPRRGNVRDP PQLEIPPPPP
YPPPCLDKCF MDSAITFRKN HVDMDNKIMK KLNDYIHLPT SILELDHNCL VEKCSSSSFP
DDACTASEGT AEDSGIVSSP SDVVHPASPE GSLRMGWQLS QGIMNDDLHQ LRDKESGWPC
QNWKLTVHFP THRHSSDFDP NQTTAGIKCD QYDEDLDLTA QLHQTLADLD ADLADVEHTD
LTSKSSTYSM DKVGFTYPCE IPVSDVDMAV PVTTIDEVYE DYRCSVTNYE IVSSQTEETI
NGKYASSFKI SSELENKNNN AVTAAVQSPR DHDNLKSIKQ SSSSYYTEEK CCTVPVTEIQ
FGTQRDNDFP TDRINSQIQK IKTDNEETPK LQSVNQYEPR ESHGNSESLA STRRQITQSK
IPQSCASRVG MKTFTVVPLK PALSQNQKPG GSLVIGAIKI DAQGNLIKPD DSENRNNGSL
CSSNDSEESL LRRAKAFWSS AEQHESDNTS RRALTKTRDL GDYDSPLAEP VQRQKLATEA
KSVNNAVKEE VSTGIPHSKP GGKNKLLTPE LMQQSLKPML KTEVKNDLSF LKPSRRTSSQ
YVASAIVKSA IRMPTAKGGS FKLVFPNENR YTYPETNYTK HTHISAEISK TKETKSDILA
LTPIQSQSFS NHKVSQYQLN KTAFEQSVSV EEKNNASGNS NLYNEKSAVS DEEIAKTRLT
ESQKSYRTLQ LQNDASRLES SFIRPIHNPL IKQTVKEDIS ELTEGDSQRP PAEFNNLTNV
NIFGPVRKFK PVTLKSIQIE TSLHSTLMEA IQSGDGKERL RKITATTGET TQKKPSFVEA
ENERAALLAA IRAQSNSSRL RKTKSTAAEE LGNIRKAEEG NGGPSTEAVL RPPHAPPPPP
PPPPAGMLKA RPSGSVLRSR GSPEQARAAL LEAIRSGSGA AHLKKVRDIC
//
