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Database: UniProt
Entry: W5LZI4_LEPOC
LinkDB: W5LZI4_LEPOC
Original site: W5LZI4_LEPOC 
ID   W5LZI4_LEPOC            Unreviewed;       694 AA.
AC   W5LZI4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   25-OCT-2017, entry version 23.
DE   SubName: Full=Potassium voltage-gated channel subfamily Q member 4 {ECO:0000313|Ensembl:ENSLOCP00000001541};
GN   Name=KCNQ4 {ECO:0000313|Ensembl:ENSLOCP00000001541};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000001541, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Ensembl:ENSLOCP00000001541, ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000001541}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSLOCP00000001541}.
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DR   EMBL; AHAT01009374; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009375; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009378; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009379; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009380; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009381; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009382; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01009383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSLOCT00000001546; ENSLOCP00000001541; ENSLOCG00000001349.
DR   GeneTree; ENSGT00550000074513; -.
DR   OMA; WAFVYHV; -.
DR   OrthoDB; EOG091G02ZT; -.
DR   Proteomes; UP000018468; Unassembled WGS sequence.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR015573; KCQN4.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   PANTHER; PTHR11537:SF4; PTHR11537:SF4; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000018468};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     95    117       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    179    203       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    241    259       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    298    324       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      177    324       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      459    646       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
SQ   SEQUENCE   694 AA;  77168 MW;  C75962282FB6B777 CRC64;
     MVGSPSNNGG MRVLSPPAAA GDRKLEFVAL TAVHTERSEP STPERGPLSH RTGLLGTPLP
     VPPGSRPNGS SSSKRYRKLQ NCLYNVLERP RGWAFIYHAF IFLLVFGCLV LSVFSTIPEH
     QKFANEGLFI LVCHHGAWVR GAWYSLSPWR RGQGCVHRSA PPPLMLFCPV LPACDVSDFI
     VFVASVAVIA AGTQGNIFAT SALRSMRFLQ ILRMVRMDRR GGTWKLLGSV VYAHSKELIT
     AWYIGFLVLI FASFLVYLAE KDSNTEFSTY ADSLWWGTIT LTTIGYGDKT PRTWLGRVLA
     AGFALLGVSF FALPAGILGS GFALKVQEQH RQKHFEKRRM PAANLIQAAW RLYSTDVNHS
     YLTATWYFYD SMLPSFRELT VLFSHLQRQR SAKKVLPISH HTLLSGLRPY GSPCLPGDSG
     KMGFRDRIRM NNSRSQALRS KASPAAPTGP AVPTGGRRSP SSESVPEATS PGRVQKSWSF
     NDRTRFRTSL RLKPRPSADV EAPAEDGAED KAPHCDVTME EVIPAVKTLI RAVRILKFLV
     AKRKFKETLR PYDVKDVIEQ YSAGHLDMLG RIKSLQTRVD QIVGRGAIQP DRKVRSEKGE
     KTPPELDPLD ELSMMGRVVK VEKQVQSIEH KLDLLLNFYT QCLKKGSALS LATMPLTLLE
     PDLTSDYHSP TDQQELFPSA NTLNISRSES STLD
//
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