ID   W5M2Z9_LEPOC            Unreviewed;      1187 AA.
AC   W5M2Z9;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=DRBM domain-containing protein {ECO:0000259|PROSITE:PS50137};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000002757.1, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000002757.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AHAT01025061; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; W5M2Z9; -.
DR   STRING; 7918.ENSLOCP00000002757; -.
DR   Ensembl; ENSLOCT00000002763.1; ENSLOCP00000002757.1; ENSLOCG00000002348.1.
DR   eggNOG; ENOG502QR6P; Eukaryota.
DR   GeneTree; ENSGT00390000006290; -.
DR   HOGENOM; CLU_275075_0_0_1; -.
DR   InParanoid; W5M2Z9; -.
DR   OMA; CKLQFTF; -.
DR   Proteomes; UP000018468; Linkage group LG17.
DR   Bgee; ENSLOCG00000002348; Expressed in muscle tissue and 12 other cell types or tissues.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.160.20; -; 3.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR027897; DUF4559.
DR   PANTHER; PTHR35083:SF3; -; 1.
DR   PANTHER; PTHR35083; RGD1565685 PROTEIN; 1.
DR   Pfam; PF00035; dsrm; 1.
DR   Pfam; PF15112; DUF4559; 1.
DR   SMART; SM00358; DSRM; 3.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   PROSITE; PS50137; DS_RBD; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN          333..398
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          969..1022
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   REGION          400..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          587..609
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..431
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1187 AA;  131983 MW;  C78D3322B5303005 CRC64;
     VMAALMQHRF TDTEYKNWLK TTMTLLLLRT RLETFLENET ETFHSQLGNK LMGQKCQARP
     PCNTKSCGPQ GTKVCPACTQ WKDEILSNHS NRKGIIYWNN SRPHLWPTEK WEVAKVYMPR
     GNKDHSKVQD FDISAFLNLM KVCTHFKKLP EVFKNNIIVT NVRNKMMHSA DMKVATQDMM
     THMQKILHLV TELKKHVPSM FELETAIKEL QRNVEQKPDL PVFESGSLVD TLLSVQKIHD
     LEQQALKEKI ESLALRFEDE KILPESHEEL CMMKEFLDQN KDLLVQLGPQ VKQLNFIFEK
     VHLHDQQLTV LTEKVDNLEK KNDEPIFSAE VVRYKNHLLE MAQKNRWPLP VFTEHAHAKG
     YTAMVEVNGQ KFEGRQVHLS VKAAHQEVAM LALRELEKQA PSLASGEDSS TQPPGPLLKP
     TDQSETSSTA TAPVFLGSVT VTLNTEVIAP DEYSEKEEAV EAAYDKLGSV FGLEVSSSGK
     SAKQKVQQHF SESGFTQPEE ILQTSPYGKF SCKLKISGPF TFKSHGSDGV SKKKLVEQQA
     ARVALTRLAG LLGWHGGPEE NHKGALKELL ESRHLAAPVI LTVTPLQNLP APSSQDPDPP
     GQKPAQGLAQ VTNHVTAEPS QELSVSSGWW TASSRAPQLL SGAGPADCKL GMPAFPGLTT
     GGQLYFASVT VPVKKVFDPA ETHRKKKDAI QGAYSILALS FGKHCCRHSA SSSTSKQVVL
     DFFAKSGLNP PVETCESVDK LFTCKLEISG NFAFQSQEGV SRKQQAEQGA AKEALARLAL
     VLGWDPACAD GNYKGRLQEL LIKHGQEKPL YQPVPGPCCD TAFPPGTGHQ VTAILGNFTS
     EISSVRESSA QASASPSDSV AMVTQLDELD ELPAQSKMPR IESPEIQRLL EKCGLQPPQV
     TSRVSVVKMF VCKVTVHLVG LGIQTQQSWS SKKEATRKSY LKLCLVLGLQ EAEEIKATML
     VKEHFKQNSY DLPTEEFTET ADKKFNCQLK VASFTVSCEG KGSSEDLAKA EASRFTLSQL
     THIFDWGLAA KVPNGEDSVG RLTTLLQETQ QSPPTFQLID TLHKATAQLN FNNFSLESSG
     HRLGSKKLTQ KEVSTRLLGL LGEIQKDDAS NSTPARNRVQ EWFDKKGWKS LKFEDTAEKH
     GVKVTFSARF DCSHQDWEPS WECAQEKLGE ELQARFKYLF EDSADQI
//