ID W5M513_LEPOC Unreviewed; 602 AA.
AC W5M513;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Polypyrimidine tract binding protein 3 {ECO:0000313|Ensembl:ENSLOCP00000003471.1};
GN Name=PTBP3 {ECO:0000313|Ensembl:ENSLOCP00000003471.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000003471.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000003471.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01012596; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01012597; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01012598; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01012599; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5M513; -.
DR STRING; 7918.ENSLOCP00000003471; -.
DR Ensembl; ENSLOCT00000003478.1; ENSLOCP00000003471.1; ENSLOCG00000002942.1.
DR eggNOG; KOG1190; Eukaryota.
DR GeneTree; ENSGT01050000244924; -.
DR HOGENOM; CLU_015171_7_1_1; -.
DR InParanoid; W5M513; -.
DR OMA; NAHYARM; -.
DR Proteomes; UP000018468; Linkage group LG2.
DR Bgee; ENSLOCG00000002942; Expressed in larva and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0043484; P:regulation of RNA splicing; IBA:GO_Central.
DR CDD; cd12784; RRM2_ROD1; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR PANTHER; PTHR15592:SF17; POLYPYRIMIDINE TRACT-BINDING PROTEIN 3; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13893; RRM_5; 1.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 108..182
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 232..308
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 408..482
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 525..600
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 72..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 602 AA; 65885 MW; 904794E4B5A21E86 CRC64;
MREQRERGRE QSESSELSCS NNTLIHLLIL LNSYCCFILV KVSSVPWMDP HKRFDQKHIP
LQLRGSDELL SSGFTNGPST MSNSTPSTAN GNDSKKFKGD RSPCAPSRVL HIRKIPLEVT
EAEVISLGVP FGKVTNLLML KGKNQAFIEM ASEDAAITMV NYYTTATPHL RNQPVFIQYS
NHRELKTDNL PNQARAQAAL QTVNAVHSGN MTLSSSASAS DGTLMPGQSP VLRIIVENLF
YPVSLEVLHQ IFSKFGTVLK IITFTKNNQF QALLQYADPM NAHHAKLTLD GQNIYNACCT
LRVEFSKLTS LNVKYNNDKS RDFTRVDLPS GDGQPTLDPS MAAAFGAPGI ISSPYAGAAG
FAPAIGFPQA AGLSMQTVPG ALGPLTIPAS AMAGRMAIPG MTPATVHSVL LVSNLNPDSI
SPHGLFILFG VYGDVHRVKI LFNKKENALI QMADATQAQL AMSHLNGQRL HGKVIRVTIS
KHQTVQLPRE GQEDQGLTKD FSNSPLHRFK KPGSKNFQNI FPPSPTLHLS NIPPSITDDN
LKDLFAGTGY TVKAFKFFQK DRKMALIQLG SVEEAIQALI DLHNHDLGEN HHLRVSFSKS
TI
//
