ID   W5M8I7_LEPOC            Unreviewed;       935 AA.
AC   W5M8I7;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=NLR family member X1 {ECO:0000313|Ensembl:ENSLOCP00000004695.1};
GN   Name=NLRX1 {ECO:0000313|Ensembl:ENSLOCP00000004695.1};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000004695.1, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000004695.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AHAT01024180; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; W5M8I7; -.
DR   STRING; 7918.ENSLOCP00000004695; -.
DR   Ensembl; ENSLOCT00000004703.1; ENSLOCP00000004695.1; ENSLOCG00000003928.1.
DR   eggNOG; KOG4308; Eukaryota.
DR   GeneTree; ENSGT00940000159493; -.
DR   HOGENOM; CLU_016769_0_0_1; -.
DR   InParanoid; W5M8I7; -.
DR   OMA; NISMMKY; -.
DR   Proteomes; UP000018468; Linkage group LG26.
DR   Bgee; ENSLOCG00000003928; Expressed in heart and 12 other cell types or tissues.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR048900; NLRX1_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF152; NLR FAMILY MEMBER X1; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF21402; NLRX1_C; 1.
DR   SMART; SM00368; LRR_RI; 5.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT   DOMAIN          98..231
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   935 AA;  105031 MW;  7940ADB2EAAAAECB CRC64;
     MRPFSSGTSN PVHADPILLH KQKLTQWFSH LPKEEKQFGV LFSPESMHVD PLILERNPKE
     SQNVDTWMKD VGVNDYQSSL TTEQLFDPVP GSYTDRGHNV VLYGSVGTGK SMVVRKLVLD
     WCRGSALSQF ELVIPFSCED LSLLGRPASL RQLVRRKYLH LRDTPLLSGE GALARQVLFI
     FNGMEQMKLD FRLSTTELCA DPDEPLPAGT ILVNLFRKYL LPEASILVTT RLSALDRIPG
     KYVNRYVQIC GFNNPDQQRA YFTSRLLHHA SGEQPSQEAE ALLRMLYLNL QSESQLAAAC
     FLPSYCWLTC ATLHFLHFTD AKAPIRTLTG IYTSFLRLNF GGEVLEASSR LGGAGGSEDQ
     QGSSLMYYVA QTVGKLAFDG VNYKRTCFSE EELEQWIGGK TKTDEELRQL AVFQTDVLDF
     FLVPYVGSSR PGEDVGETRY VFAIPAMQEY LAALYVVLGE NKTVLEKLGK QASEAIGQAS
     EDLTSLLNIL SKFLPLRIFA IFNLLKMFPS LYRRVSGHGK GRIARTMAAE MFRKEDQFNA
     DVLDQVEQSV LGVQGPLPQE RQEKEAFELY PVFMGGLLSY GNRVLLDQLG CTIKSTAVAQ
     ITSTLKKNLV KESQKHQPPE EMMDLLFFLY EFQNPRFTAE VLGSLKAISL ARVRMTPLKC
     YVLRCVLSCA PSKHLLKELD LSSCHLTKDL LETLGPSLLR ARSLNLQFNN LGPDACPQLK
     ELLLDSRCQI RTLRLCDNSL LEPGVSCLLE ALSENRSLRH LSLMHTGMGD GGARELAARL
     RDNKGLEELN VAYNAIGDSA AVQLVDTCRE HPTINTVHLY LNQLSEAGKQ SLHARAQRGE
     GPSRRVKVLA SVTEGGELSE DWHPILGIIR QNCTSWERPR VREQLLLFLR DLEGGRRQTR
     SLAKKLYFRR VERDVKQTLR MLEEHSIAVL KGCTN
//