ID   W5MDV7_LEPOC            Unreviewed;       828 AA.
AC   W5MDV7;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 3 {ECO:0000256|ARBA:ARBA00020976};
DE   AltName: Full=Component of oligomeric Golgi complex 3 {ECO:0000256|ARBA:ARBA00031339};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000006566.1, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000006566.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Involved in ER-Golgi transport.
CC       {ECO:0000256|ARBA:ARBA00002090}.
CC   -!- SIMILARITY: Belongs to the COG3 family.
CC       {ECO:0000256|ARBA:ARBA00009936}.
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DR   EMBL; AHAT01020396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHAT01020397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; W5MDV7; -.
DR   STRING; 7918.ENSLOCP00000006566; -.
DR   Ensembl; ENSLOCT00000006574.1; ENSLOCP00000006566.1; ENSLOCG00000005428.1.
DR   eggNOG; KOG2604; Eukaryota.
DR   GeneTree; ENSGT00390000015682; -.
DR   HOGENOM; CLU_011639_1_1_1; -.
DR   InParanoid; W5MDV7; -.
DR   OMA; DEFELWG; -.
DR   Proteomes; UP000018468; Linkage group LG17.
DR   Bgee; ENSLOCG00000005428; Expressed in muscle tissue and 13 other cell types or tissues.
DR   GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR   GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   InterPro; IPR048685; COG3_C.
DR   InterPro; IPR048320; COG3_N.
DR   InterPro; IPR007265; COG_su3.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   PANTHER; PTHR13302; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; 1.
DR   PANTHER; PTHR13302:SF8; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3; 1.
DR   Pfam; PF20671; COG3_C; 1.
DR   Pfam; PF04136; COG3_N; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          130..272
FT                   /note="Conserved oligomeric Golgi complex subunit 3 N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04136"
FT   DOMAIN          293..641
FT                   /note="Conserved oligomeric Golgi complex subunit 3 C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20671"
SQ   SEQUENCE   828 AA;  94353 MW;  A658AB84BFBDBA7F CRC64;
     MAAVDVSVLD QSEKETREKL SLWDRRSDPM APLTERQTDS ILEVRAAAEN LPIPSEQLPI
     EDLCSLTSRS LCAPLSTTVP ASTEDVLFKG FQSLGMENER IETAQQFFSW FSKLQTRVDQ
     DEGAKNRLTR DHLSGFQDQC DAILNDVNTA LQHLDSLQKQ YLFVSTKTGT LHEACEQLLK
     EQSELVDLAQ SIQQKLSYFN ELENINAKLN SPTLSVNSEG FIPMLSKLDD CIEYVSSHPH
     FKDYPVYLAK FKQCLSKAMH LMKTHTVNTL QNLTTQLTKR DPSGVPSSEN AFTLYYVKFR
     ASAPKVRTLI EQIEQRSEKI PEYQQLLGEI HQCYLDQREQ LLSPSITSTI TDLTSQNNKD
     HCALVRSGCA FMVHVCQDEH QLYNEFFSKP TVKLDELLER LCLSLYDVLR PLIIHVIHLE
     TLSELCGILK NEMLEDHVQN NMQQLGAFEA VVKQMLEDVQ ERLVYRTHIY IQTDIIGYNP
     APGDLAYPDK LEMMEKIAQS LKEEQKKQLS LDSSFSDVQL EDADSKNVIK SGTGEAPGAR
     LHASISPADL HGMWYPTLRR TLVCLSKLYR CIDRAVFQGL SQEALSSCIQ SLLKATDAIT
     KNKTQIDGQL FLIKHLLIMR EQIAPFHTDF AIKEISLDLK KTKDAAFKIF NPRTVPKFFR
     LNSHNAILQF LLEGTPEIKE HYIDSKKDVD RHLKSSCEQF IQQQTRLFVG NLEEFLTKVT
     ALKTMANQGG PSYNLPQQPW AQPAKINELL TATYRTMKTK LPTTSQSMSL YLANRDTEFI
     LFKPVRNNIQ QVFQKLHTVL QEEYSGEDLQ IIACPSMEQI NLLLSVNK
//