ID W5MFD9_LEPOC Unreviewed; 808 AA.
AC W5MFD9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=MTSS I-BAR domain containing 2a {ECO:0000313|Ensembl:ENSLOCP00000007098.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000007098.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000007098.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01020949; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MFD9; -.
DR Ensembl; ENSLOCT00000007106.1; ENSLOCP00000007098.1; ENSLOCG00000005856.1.
DR GeneTree; ENSGT00950000183156; -.
DR HOGENOM; CLU_004805_2_0_1; -.
DR Proteomes; UP000018468; Linkage group LG23.
DR Bgee; ENSLOCG00000005856; Expressed in camera-type eye and 10 other cell types or tissues.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07643; I-BAR_IMD_MIM; 1.
DR CDD; cd22060; WH2_MTSS1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF8; PROTEIN MTSS 2; 1.
DR Pfam; PF08397; IMD; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 1..249
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 780..797
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 253..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 615..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..776
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 808 AA; 86624 MW; 6B67E3895C5DD491 CRC64;
METVEKECGA LGGLFQAIVN DMKSSYPIWE DFSAKATKLH SQLRTTVLAA VAFLDAFQKV
ADMATNTRGA TRDIGSALTR MCMRHRSIEA KLRHFTNALM ESLITPLQDR IEDWKKTANQ
LDKDHAKEYK RARHEIKKKS SDTLKLQKKA RKGRGDLQPQ LDSALQDVND MYLLMEETEK
QAVRRALVEE RGRFCTFISL LQPVVNGEIA MLGEITHLQA IIDDLTVLTA DPHKLPPASE
QVIKDLKGSD YSWSYQTPPS SPSSSGSRKS SMCSSVNSAH SSASRSSSGS QTHSPSSSYR
YRSLAQPPPG GAQRLSSVSS HDSGFISQDA AVYSKPPSPM PSDITSQKSS SSASSEASET
CQSVSECSSP TSFGSSFATF RPAISHTGSI RPFSVILPAS PPYNCPPGSN TYSPTSKVPC
WKDWSKPGPY DQPLVSTLQR RKEPIERLRE SEQGPPPPGY AGLHPEDPQR TRMTPATIAA
KHGEEVSPAA SDLAMVLTRG LSMEHQKSSR DSLQYSSGYS TQTTTPSCSE DTIPSQVSDY
DCYSVNGDAE GDVQTEFDKS STIPRNSNIA QNYRRMIQTK RPASTAGLPS GVGAPGAHPG
GGGGGGGGSG TPGVATIRRT PSTKPSVRRT LSNAGPIPIR PPIVPVKTPT VPDSPSYTGP
PARVGSEECV FYADDTSPNA MDYVKASPKR LSLPNTAWGS GAGLEMSVYA QPPPPLSTEE
DLLLAANRHS LVEKIGELVA SAHALGEGQF PFPSLPGDDP GSDPQAPPPG PAPSQDPAPG
GEDMLVAIRR GVRLRKTLTN DRSAPRIL
//
