ID   W5MJV9_LEPOC            Unreviewed;      1373 AA.
AC   W5MJV9;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Baculoviral IAP repeat-containing protein 1e-like {ECO:0000313|Ensembl:ENSLOCP00000008668.1};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000008668.1, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000008668.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AHAT01020295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015219367.1; XM_015363881.1.
DR   RefSeq; XP_015219368.1; XM_015363882.1.
DR   RefSeq; XP_015219369.1; XM_015363883.1.
DR   RefSeq; XP_015219370.1; XM_015363884.1.
DR   STRING; 7918.ENSLOCP00000008668; -.
DR   Ensembl; ENSLOCT00000008678.1; ENSLOCP00000008668.1; ENSLOCG00000007157.1.
DR   GeneID; 102686781; -.
DR   KEGG; loc:102686781; -.
DR   eggNOG; KOG1101; Eukaryota.
DR   GeneTree; ENSGT00940000163559; -.
DR   HOGENOM; CLU_005648_0_0_1; -.
DR   InParanoid; W5MJV9; -.
DR   OrthoDB; 5404838at2759; -.
DR   Proteomes; UP000018468; Linkage group LG17.
DR   Bgee; ENSLOCG00000007157; Expressed in pharyngeal gill and 8 other cell types or tissues.
DR   GO; GO:0072557; C:IPAF inflammasome complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IBA:GO_Central.
DR   GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR   GO; GO:0016045; P:detection of bacterium; IBA:GO_Central.
DR   GO; GO:0006954; P:inflammatory response; IBA:GO_Central.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0070269; P:pyroptosis; IBA:GO_Central.
DR   CDD; cd00022; BIR; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001370; BIR_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR028789; Naip.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46914; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46914:SF1; BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00653; BIR; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   SMART; SM00238; BIR; 3.
DR   SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS01282; BIR_REPEAT_1; 2.
DR   PROSITE; PS50143; BIR_REPEAT_2; 3.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT   DOMAIN          459..500
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          360..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        360..376
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1373 AA;  156067 MW;  B64FC0452374A771 CRC64;
     MAAEIPNTTQ DPQEEDYFSR KEVDFSEHVF SFLNHNSIKI QEDNEKMYQT VRKQKGRRYN
     HQMRSELERI KTMQESEAFG DPSGLAEAGF YSIEGDKAMQ CFCCGVVIGQ IGLQKRAMEK
     HREWDPNCGF VKGDDVGNIP KYDVRVQVSE AWSRNSGQKF NTKQQRVESF HNWPFYAQLD
     PSLLAEAGFF YTGTKDHVLC FCCGGCLGHW GADDDPWEEH AKWFPECEYL QTKKTTDEIL
     DYINQYNAFK GVKGSHFKNR KKTPEERTCS TDLEEKLNIF ADENLRLESF LMWPSDSSAD
     PKALSQAGFF YTGTDDKVKC FLCGTEVFKW EDGDVPFEEH QKWSPQCPFV LDKQQHHAFE
     EMKSESTSKK NNLQDQEPEF PECNPITEDV RTFEDRLSNF LRNVYSSLSF CKPAVVEDVS
     CFAIDLKKVF VDLAMTSQEQ KGSSAQSVTL PELLRSLDGL TVVKGGRGTG KTALLKKIAI
     LWASDYCPVL SRFQFVFYVS FSNLNASPAL VSVKANLERM MKQYGESALF LLDDVGEGEN
     PLLEKLREKL QSQERPHCLS MVIAICPYMM DRINLLPDRT VTLKDFPTCR SACLVKRLIW
     PNLSIMKKCL EKLWFYSFKA SLKTPFCALA LCISLVQKPG MNLSTGSSFY STFVQYLMQG
     IDENSKLLLV EQLAWEGLMR NQFEFTDKDL TNLGLQSGWL IKQGLVVEGN CGPHSLRFID
     EYFQEYLAGR YLAHLFNSDQ IEKASICLSQ IMPFPKALGQ FYLLLLHCFH HSGKAATVII
     PQLLAQYSCL DAWMSADTDK GLHKQSSSPR SLIRILTQCV KMCAEFFDGS TTHWKSSMID
     GNIFYLINVE RVLKLIYESN CTSVGFPIIR QHLAGTTLHF DSPMYPILCV LYFLKDYPQC
     IPELQCTRVT FSDVLDCVET DPSQPHSWKF VQLPVEFVSA FQAAYQQKVT GEKLHLAANR
     VASFEKNDVL RLSVLFSVFK RIDIEVEDSP GFLSWIQCIL DKFRESWVRC RIIGCSLAQE
     DRKCLLSATE LKVLELVGTA ASPVSEYILR HLDKFTALEE LQVSVSPPSQ VVEKIPLGFR
     NLVNLRSIKL YNIDLTEDTS SLAWFIRHFS CLTVFHLRCA SCPGFEQLAK ALSSCKGLQE
     LKLGSFTLNE TETQTLASLL SNLQSLRILS LWRLKVEADS AVETFANALE TLSQLECLKV
     PALTQRSELI VEKLHLFSEL QSLRMDCCLN DDSLNRLAQT ARAGHLCRLQ KLVLNDHQAV
     TDVGWKGFFQ GLGGLEELRS FSLSQKSPAA AAVDPGADTV QALMQCVSRM PCLRLLLLLG
     WFSKKEDSEP VRGLKQSHPN LDIDLRFKDL QLPAEIRMVL LEVINGIRQC HFT
//