ID W5MPM6_LEPOC Unreviewed; 331 AA.
AC W5MPM6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000010335.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000010335.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein
CC {ECO:0000256|RuleBase:RU363063}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661, ECO:0000256|RuleBase:RU363063}.
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DR EMBL; AHAT01007571; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MPM6; -.
DR STRING; 7918.ENSLOCP00000010335; -.
DR Ensembl; ENSLOCT00000010348.1; ENSLOCP00000010335.1; ENSLOCG00000008492.1.
DR eggNOG; KOG2287; Eukaryota.
DR GeneTree; ENSGT00940000163421; -.
DR HOGENOM; CLU_036849_2_1_1; -.
DR InParanoid; W5MPM6; -.
DR OMA; KYDRCTF; -.
DR Proteomes; UP000018468; Linkage group LG6.
DR Bgee; ENSLOCG00000008492; Expressed in intestine and 13 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; IBA:GO_Central.
DR GO; GO:0006493; P:protein O-linked glycosylation; IBA:GO_Central.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR045821; B3GT2_N.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11214:SF361; HEXOSYLTRANSFERASE; 1.
DR Pfam; PF19341; B3GALT2_N; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363063};
KW Golgi apparatus {ECO:0000256|RuleBase:RU363063};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 49..78
FT /note="Beta-1,3-galactosyltransferase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19341"
SQ SEQUENCE 331 AA; 38073 MW; B9FF0391AF96E814 CRC64;
YLIESLSNVK NEDIRLLVLP LRSSGLLSLL IYLVWFPREQ HQRQQLVESK LYKVISPSTY
RYILNEPDKC RDMSPFLILM IPVAPTDRAA RDAIRKTWGR EGLIPGVIIG RIFYVGLPQG
DQAPRIQVAL EEESREHRDI VQKDFLDSYR NLTIKTMMIL DWLATYCPGA SYAMKIDTDM
FLNVDYLVNK VLDTRSVPAK EDFITGAVIA DGRPRRSKES KWYMPEDAYP EDTYPPYVSG
TGYVFSVGLA KKLLSASKFV RPVPLEDIYL GLCLQVLGVL PRRSSWWHSL FNIQSMAYER
CIFSQLVTVT GYTPSKLLHV WHDFSKAKFT C
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