ID W5MQY6_LEPOC Unreviewed; 1418 AA.
AC W5MQY6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Neurexin 3a {ECO:0000313|Ensembl:ENSLOCP00000010795.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000010795.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000010795.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AHAT01003919; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01003920; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01003921; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01003922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSLOCT00000010810.1; ENSLOCP00000010795.1; ENSLOCG00000008835.1.
DR GeneTree; ENSGT00940000154618; -.
DR Proteomes; UP000018468; Linkage group LG7.
DR Bgee; ENSLOCG00000008835; Expressed in camera-type eye and 9 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF57; NEUREXIN-3; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1418
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004866640"
FT TRANSMEM 1398..1417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..198
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 194..231
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 259..449
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 456..648
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 652..689
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 694..866
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 880..1055
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1067..1104
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1108..1308
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1339..1362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1418 AA; 157116 MW; 4F3A72623EE54C5A CRC64;
MNPICFSLKV HLLLSALLGL CLGLEFAGTP GQWARYLRWD ASTRSDLSFQ FKTDVSTALL
LYFDDGGYCD FLQLMVVEGK LQLQFSIDCA ETTIVSDKRV NDSNWHFAMV SRNNLRTVLV
VDSETKADEV RPERQYMKIV SDLFIGGVPQ DIRSPALTLP SVKNQSPFKG VITDLKYGNK
EPTLLSKRMV SLDMEGMCSE NLCENGGSCS VVKGEPKCDC SNTGYIGQFC SEAEVNNIPG
FAHLMMAEQG RSKAREENVA TFRGSEYFCY DLSQNPIQSS SDEITLSFKT WQRNGLILHT
GKSADYVNLA LKDGAVSLVI NLGSGAFEAI VEPVNGKFND NSWHDVKVTR NLRQHSGIGH
AMVTISVDGI LTTTGYTQED YTMLGSDDFF YVGGSPSTAD LPGSPVSNNF MGCLKEVVYK
NNDIRLELSR LARIIDPKMK IQGDVVFKCE NVATLDPISF ETPEAYISLP KWNTKRMGSI
SFDFRTSEPN GLILFTHGKP QDRKDSRSQK NTKVDFFAVE LLDGSLYLLL DMGSGTIKVK
ATQKKVNDGE WYHVDIQRDG RSGTISVNSR RTPFTASGES EILDLEGDMY LGGLPENRAG
LILPTELWTA MLNYGYVGCI RDLFIDGRSK DIRQIAEAQN GAGIKPSCTK VNGKQCESYP
CRNNALCKEG WNRFICDCTG TGFWSRTCER EASILSYDGS MYMKVVMPTV MHTEAEDVSL
RFMSQRAYGL LMATTSRDSA DTLRLELDGG RVKLTVNLDC IRINCNSSKG PEILYAGQKL
NDNEWHTVQV VRRGKRLKLV VDDDMAEGQM VGDHTRLEFH NIETGIMTER RFISVIPSSF
IGHLQSLKFN GMLYIDLCKN GDIDYCELNA RFGMRSIIAD PVTFKTKSSY LSLATLQAYT
SMHLFFQFKT TTPDGFILFN SGDGNDFIAV ELVKGYIHYV FDLGNGPNVI KGNSDKALHD
NQWHNVVITR DNSNTHTLKV DAKAVTQVIN GAKNLDLKGD LYIAGLGQGM YSNLPKLVAS
RDGFQGCLAS VDLNGRLPDL INDALYRSGQ IERGCEVEFT KADLQGPSTT CQEDSCGNMG
ICIQQWENYT CDCSMTSYAG TQCNDPGATY IFGKGGGLIT FTWPSNDRPS TRTDRLAVGF
STSLKDGILV RVDSAPGLGD FLQLHIEQGK IGVTFNIGTV DISIQETSAP VNDGKYHVVR
FTRNGGNATL QVDNWPVNEH YPTGSSDYER LQMVNKKIPF KYTRPVEEWL QEKGRQLTIF
NTQATITIGG NDRKRPYQGQ LSGLYYNGLK VLNMAAENNP NIKINGSVRL VGDVPSVHGS
ATTTSVPPEM STTFIETTTT MSTTTTRKHR SPPTIQTTDD IVSSAECSSD DEDLEECDSG
HTAKSSNAAR LLRTAFTWKW QLTFTFTLII LISYAVCS
//
