ID W5MW13_LEPOC Unreviewed; 1265 AA.
AC W5MW13;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=SH3 domain and tetratricopeptide repeats 1 {ECO:0000313|Ensembl:ENSLOCP00000012572.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000012572.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000012572.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01001251; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MW13; -.
DR Ensembl; ENSLOCT00000012595.1; ENSLOCP00000012572.1; ENSLOCG00000010260.1.
DR GeneTree; ENSGT00530000063812; -.
DR HOGENOM; CLU_004832_0_0_1; -.
DR Proteomes; UP000018468; Linkage group LG4.
DR Bgee; ENSLOCG00000010260; Expressed in mesonephros and 12 other cell types or tissues.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR042772; SH3TC1/SH3TC2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR22647:SF3; SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR22647; SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 233..296
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REPEAT 1123..1156
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 376..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..400
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1265 AA; 144555 MW; 4D35829D17DD7694 CRC64;
MESGFGNKSK DAAIFMKLVM VRRKTGLPDE ELQEMLRGKL RILENDSGEV MALFSELSAR
LLSIHSEEDI IVVTFKTFEE IWKFNTYYSL GLLGHCMENL LLDQVFWLHH LDEEDLGIEV
LIHEETLHLM YKGILMQEES FFAVCTAEQN CESASTGSEL RLQEGNVAIF EPPSDGSEWT
VQLLVDGSRG SIAKPALEPV SPFHQWFLKA CPENILMGNA KLLCEFPYQF VTSAVGSCIA
TVGYEGSGPD ELSFKSGDCV EIVGFLVSCF EWFVGKHSET GRTGLVKTSL VKPTNSICES
AEVFLSEEEE SLFKWKEEFF EEKSIDVLKK MCQTDVDAVY KLGKIIASTF NNESDPQRQE
LQNKIAVCLS RLKEPHVPPK ETQHEDRQSE HHHNHSLSSK EHSEPCFIIN SEGDNHSADD
FQTLLAFLNC SEYKEEFRNI YDFSFRFLQS MFQGYTDDEE LVFYLGMARE NARKKKFLWA
QTRICFLLGK LCARRLKFSQ ARVYFEEALS VAREQFKDIF LLISIYTNLA AIYLKQKNKE
KYVAIFERIA AFLMGIPNYI CSTEQESEIL KYVLKKAVLA QNKVAEVRTC FLLAKLYTKL
NQPQSALLFT ERLQILAKEL SLTSKVMPSD YYLTLGKLYG AKYLPHLAVS SVKQAVFHTG
ATLTDCLIGT EFVMDNASRL YSLGKCGVLV PTQVAPYLNK ALYFAADKKD QVLCQTISLC
LSHLHQYHGM LNKAIWYIDT VISKNVWPSA THAANILIHL AWLHILNRQH HMALDILTSG
LGSLSEHCTK LQKGLVYNMR AVALRYTEDI KQAAESYGKA IQICEESDFK YNRAIAQANF
GFLCLHAKAK GLAELSLVRA VELFSQLEDV AHEENFITVL LELGQYYVSQ TQLEKGMICY
EWAFLMAIKA NHVECQLQAT KQLCHFYHMI CPNEAQCIIY NEYMLTLVRK AGNKEWEGQI
LETISQLYFS LGTERAYKSA LDYTKRSLGI FIDLRKKEKE AYAWLQAGKI YHILRQNELV
DLYIQVAQDC CLSTADMHFV LELLEAAGDV FFNSSQDREK ALTFYRDKAL PIALKTGNVK
TQLRLSNKLA ELLLQLKFYG EAVDHAQAAL AISISLGERL NERVAFHRLA TLFHCLGQYE
MAEHYYLKAL SLCPSPLEFD EETMYYVKVY QLLGDMIFYD LKDPYDAAGY YHLALAAAMD
LGNKKSQLKL CTRLATIYHN FLINRELSLF FYQKARVFAA DLNVRRINLS PDQYYQSVSQ
YKTFV
//
