ID W5N581_LEPOC Unreviewed; 1995 AA.
AC W5N581;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Sidekick cell adhesion molecule 2 {ECO:0000313|Ensembl:ENSLOCP00000015790.1};
GN Name=SDK2 {ECO:0000313|Ensembl:ENSLOCP00000015790.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000015790.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000015790.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01000375; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7918.ENSLOCP00000015790; -.
DR Ensembl; ENSLOCT00000015820.1; ENSLOCP00000015790.1; ENSLOCG00000012818.1.
DR eggNOG; KOG3510; Eukaryota.
DR eggNOG; KOG4221; Eukaryota.
DR GeneTree; ENSGT00940000155761; -.
DR InParanoid; W5N581; -.
DR OMA; WFMVTLA; -.
DR Proteomes; UP000018468; Linkage group LG10.
DR Bgee; ENSLOCG00000012818; Expressed in camera-type eye and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 13.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 17.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF46; PROTEIN SIDEKICK-1 ISOFORM X1; 1.
DR Pfam; PF00041; fn3; 13.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 13.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 7.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 13.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1732..1755
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..99
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 110..200
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 204..293
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 298..389
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 394..490
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 495..591
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 596..695
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 699..793
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 797..896
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 901..999
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1004..1101
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1105..1199
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1204..1301
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1306..1423
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1428..1524
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1528..1623
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1626..1724
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 480..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1811..1830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1842..1870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1898..1995
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1842..1862
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1914..1931
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1932..1978
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1995 AA; 219852 MW; 4B05A125AB3ACD57 CRC64;
PVTLTENVGG PADPIAPTII IPPRNTSVIS GTSEVTMECV ANARPLIKLS ISWRKDGVLV
TSGLSDFNRQ LTILSPAVSD AGFYECEAIL RSSSVPSVSA GAYLHVLEPP QFVKEPDRHI
TAEMEKVVDI PCQARGVPQP EIVWYKDAVP VSHVKTLRYR VLSGGSLQVN GLLPDDTGMF
QCFARNPAGE VQTNTYLAVT SIAPNITAGP SDSTVIDGMS VILHCETSGA PRPAITWQKG
ERILASGSVQ LPRFTLLESG SLLISPSHIS DAGTYTCMAS NSRGIDEASA ELVVWARTRI
TSPPQDQSVI KGTKAILTCG VTHDPSVTVR YTWEKGSSVI NPDSVPRIRM DPDGTLHISQ
TWSGDIGTYT CHVTSVGGND SRSAHLRVRQ LPHAPENPVA TLSLIEKRAI NLTWAKPFDG
NSPLIRYILE VSENNAPWTV LLANIEPESN MVTVGGLIPA RSYQFRICAV NDVGKGQFSK
ETDRLSLPEE PPSAPPQNVI ASGRTNQSIM IQWQPPPETH QNGILRGYII RYCLAGLPVE
YQFKNITNPD VTNLLLEDLI IWTNYEIEVA AYNGAGLGVY SHTVTEWTLQ GVPTVPPGNV
QAEAVNSTTV RFTWTPPSPQ FINGINQGYK LLAWEPGKEE EVTVVTVRPN FQDNVHVGYI
TGLKKFTEYF SSVLCFTTPG DGPRSASHAL RTHEDIPGAV GHLSFTEILD TSLKVSWREP
NEKNGILTGY RISWEEYNRT NTRVTHYLPN VTLEYRVTGL TALTTYTIEV AAMTSKGQGQ
LSSSTISSGV PPELPGPPTN MAISNIGPRS VTLQFKPGYD GKTSISRWQV EAQITVIGEN
EEWVLVHQVP NEPDARSLEV PNLNPYTFYR FRMRQVNIVG TSPPSQPSRK IQTLQAPPDI
APANVTLRTA SETSLWLRWV PLPEWEYNGN PEFVGYRVQY SRTGAQGRAL THVIQDRLER
EFTIEDLEEW TEYEVRVQAL NGIGAGPWSQ PVRGRTRESV PSCGPTNITA FATTSSSILI
RWHEVPEPDR NGLILGYKVV YKEKDSDSPL RFWTVEGNAT QSVQLTGLGK YVLYQIQVLA
FTRIGDGVPS KPPILERTLD DVPGPPVGIL FPEVRTNSVR LIWQSPAQPN GIILAYQITY
RLNSTSSNTA TVEVLNPSTR QFTVTGLKPE SVYVFRITAQ TRKGWGEVAE ALVVTTEKRA
RPQPTSRPTV QQENVQARSV LLSWEPGSDG LSPVRYYTVQ LRELPNKNWT VHSASVSHEA
TSYIVNRLKP FTSYQFRVKA TNDIGDSEYS EESEAITTLQ DAPDAAPVIL SVTPHTTTSV
LIRWQPPSEE HINGILLGFR IHYRELLYER LRSFTVRTFN GPTATWAELT SPYSVRNLTE
SSLTQYELDN LSKHKRYEIR LSVYNAVGEG PTSAPQEVFV GEAVPTAPPQ NVAIQSATAT
QLDVTWDPPP LEAQNGDIQG YKIYFWEFQR QNQTERLRTL FLPEGGVKLK NLTGYTTYMI
SVAAFNAAGD GPRSPATRGR TQQAAPSAPS FIHFSELTTT SVNVSWGEPV HPNGIIEGYR
LIYEPCTPVD GVSKIVTVDV KGSAPLWMKI KDLADGVTYN FRIRAKTFAY GPEVEANITT
GPGEGAPGPP GEPFISRYGS ALTLHWANGD PGRAPITRYV IEARPSDEGL WDILIKDIPK
EVTSYTFNMD ILKQGVSYDF RVIGVNDYGY GSPSAPSPSI SAQKVAPFYE EWWFLVVVAL
VGLIFILLLV FILIIRGQSK KYAKKSDSGN NSNCNALSHG EMVSLDEGRF PALELNNRRL
SVKNSFCRKN GVYTRSPPRP SPGSLHYSDE DVSTKYNDLI PAESSSLTEK PSEISDSQGS
DSEYEVDQNR QKTHSFVNHY ISDPTYYNSW RRQQKGISRA QAYSYTESDS GEPEHCAPPP
PLPPLPPLPP QLNNTAQAQA QAQAQGSLFR PKGSRTPTPQ QQPSNPPSQH STLYRPPSSL
APGSRAPIAG FSSFV
//
