ID W5N586_LEPOC Unreviewed; 446 AA.
AC W5N586;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Zinc finger FYVE-type containing 19 {ECO:0000313|Ensembl:ENSLOCP00000015795.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000015795.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000015795.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01019019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015206353.1; XM_015350867.1.
DR AlphaFoldDB; W5N586; -.
DR STRING; 7918.ENSLOCP00000015795; -.
DR Ensembl; ENSLOCT00000015825.1; ENSLOCP00000015795.1; ENSLOCG00000012832.1.
DR GeneID; 102690881; -.
DR CTD; 84936; -.
DR eggNOG; KOG1818; Eukaryota.
DR GeneTree; ENSGT00390000016108; -.
DR InParanoid; W5N586; -.
DR OMA; CDGELFC; -.
DR OrthoDB; 1459288at2759; -.
DR Proteomes; UP000018468; Linkage group LG7.
DR Bgee; ENSLOCG00000012832; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR GO; GO:0032154; C:cleavage furrow; IBA:GO_Central.
DR GO; GO:0030496; C:midbody; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IBA:GO_Central.
DR GO; GO:0009838; P:abscission; IBA:GO_Central.
DR GO; GO:0044878; P:mitotic cytokinesis checkpoint signaling; IBA:GO_Central.
DR CDD; cd19817; Bbox1_ANCHR-like; 1.
DR CDD; cd15749; FYVE_ZFY19; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR044553; Bbox1_ANCHR.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46603; ABSCISSION/NOCUT CHECKPOINT REGULATOR; 1.
DR PANTHER; PTHR46603:SF1; ABSCISSION_NOCUT CHECKPOINT REGULATOR; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 17..76
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 101..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 49307 MW; 1D1A313D270A9A3B CRC64;
MKATSPFCLD LGLVWMNDMD SRCYGCASKF SLFKKEAACK NCGRSYCAGC LGYSCLVPRC
GNTQQKVCKQ CHGNLTSGGT LNNAAKWSPP ENYKKRVAAL EAKQSQQGPA SRPSSKSIAP
RLPVARGLSK EDQAIAERLE RLKEDTTPRS IPSEKEIESR LAALKVPARP IPTAAEMEDR
LAALQGVTPP SQVPRPIHQP PDARTQTEQA SDLITQLSEE VAIDNRFAPE SGSEGVTDGP
LNNLNKADST LDENLDDLRQ DAKQLESEKS RLLAEAMEEL KQENLGREQV LQMARRLALL
KGQDPGKITA NDFSQPDSEE ETEEESLKRI LKQLSEEAAL DEASGYNILP EQSGPINTEK
PTGHKKMPCA PQSRANKKIA AAAPPSDSDE EELPWCCICN EDATIRCRSC DDELYCKRCF
REGHDDFDRK DHRTTSYKAP RKSKKK
//
