ID W5N5Q9_LEPOC Unreviewed; 615 AA.
AC W5N5Q9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=RNA-binding protein 47 {ECO:0000256|ARBA:ARBA00015191};
DE AltName: Full=RNA-binding motif protein 47 {ECO:0000256|ARBA:ARBA00030579};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000015968.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000015968.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RRM RBM47 family.
CC {ECO:0000256|ARBA:ARBA00005319}.
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DR EMBL; AHAT01001963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01001964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015201238.1; XM_015345752.1.
DR RefSeq; XP_015201239.1; XM_015345753.1.
DR RefSeq; XP_015201240.1; XM_015345754.1.
DR RefSeq; XP_015201241.1; XM_015345755.1.
DR RefSeq; XP_015201242.1; XM_015345756.1.
DR RefSeq; XP_015201243.1; XM_015345757.1.
DR AlphaFoldDB; W5N5Q9; -.
DR STRING; 7918.ENSLOCP00000015968; -.
DR Ensembl; ENSLOCT00000015998.1; ENSLOCP00000015968.1; ENSLOCG00000012966.1.
DR GeneID; 102690533; -.
DR CTD; 54502; -.
DR eggNOG; KOG0117; Eukaryota.
DR GeneTree; ENSGT00940000156979; -.
DR HOGENOM; CLU_022960_4_2_1; -.
DR InParanoid; W5N5Q9; -.
DR OMA; RTGYTMI; -.
DR OrthoDB; 3184171at2759; -.
DR Proteomes; UP000018468; Linkage group LG4.
DR Bgee; ENSLOCG00000012966; Expressed in intestine and 12 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd12485; RRM1_RBM47; 1.
DR CDD; cd12491; RRM2_RBM47; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR047044; RBM47_RRM1.
DR InterPro; IPR034440; RBM47_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF6; RNA-BINDING PROTEIN 47; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 98..176
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 178..260
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 273..345
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 67272 MW; C89644C96B6987CF CRC64;
MVSQTVAEVS FSSETSNRPQ NKLNGFGIMT AEDSAAAMSN SSSNKSACKV PEGVAGAPNE
SALLALMERT GYGMVQENGQ RKYGPPPGWE GPSPPRGCEI FVGKIPRDVY EDELVPVFES
VGRIYEMRLM MDFDGKNRGY AFVMYTQKHE AKRAVRELNN YEIRPGRLLG VCSSVDNCRL
FIGGIPKTKK REEILEEISK VTEGVLDVIV YASAADKMKN RGFAFVEYES HRAAAMARRK
LMPGRIQLWG HQIAVDWAEP EIDVDEDVME TVKILYVRNL MIETSEETIR KIFSQFNPGC
VERVKKIRDY AFVHFTGRDD AVNAMDKLNG SEVEGSCIEV TLAKPVDKEQ YTRYQKAAKG
VTPTQETPQA NYVYQCDPYT LAYYGYPYNA LIGPNRDYFV KAGTVRGRGR GAAGNRAPGP
RGSYLGGYSA GRGIYSRYHE GKAKQQQEKP YELVPSLELT AVNPVGIKPG TMALPTLGAQ
YPVFSAGPAT KLMEDGKIHA VEHLMNPIAV QHDPSAAPTA AVMPAVSTPP PFQGRPITPV
YTMAHNIQRI PATTLYGASY VPIAAPASTA TLAALQKNAA AAAAAAAYGG YASYVPQAFP
TATFQVPIHD VYQTY
//
