ID W5N7P9_LEPOC Unreviewed; 2000 AA.
AC W5N7P9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Envoplakin {ECO:0000313|Ensembl:ENSLOCP00000016658.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000016658.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000016658.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01000482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01000483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006635532.1; XM_006635469.2.
DR STRING; 7918.ENSLOCP00000016658; -.
DR Ensembl; ENSLOCT00000016688.1; ENSLOCP00000016658.1; ENSLOCG00000013503.1.
DR GeneID; 102684343; -.
DR KEGG; loc:102684343; -.
DR CTD; 373136; -.
DR eggNOG; KOG0516; Eukaryota.
DR GeneTree; ENSGT00940000153578; -.
DR HOGENOM; CLU_001780_0_0_1; -.
DR InParanoid; W5N7P9; -.
DR OMA; TEHACGA; -.
DR OrthoDB; 5357436at2759; -.
DR Proteomes; UP000018468; Linkage group LG10.
DR Bgee; ENSLOCG00000013503; Expressed in zone of skin and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005198; F:structural molecule activity; IBA:GO_Central.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0042060; P:wound healing; IBA:GO_Central.
DR CDD; cd00176; SPEC; 1.
DR Gene3D; 1.20.58.60; -; 4.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF7; ENVOPLAKIN; 1.
DR Pfam; PF00681; Plectin; 3.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 1.
DR SMART; SM00250; PLEC; 7.
DR SMART; SM00150; SPEC; 2.
DR SUPFAM; SSF75399; Plakin repeat; 2.
DR SUPFAM; SSF46966; Spectrin repeat; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 386..450
FT /note="Desmoplakin SH3"
FT /evidence="ECO:0000259|Pfam:PF17902"
FT REGION 483..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 28..55
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 650..719
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1240..1327
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1365..1429
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1455..1489
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1513..1582
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1615..1656
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 483..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2000 AA; 230543 MW; 55FC6D6B51749A74 CRC64;
MFKKKDSNTL KVSGKMSKAQ ASDLALLIAR MQKSADQVER DVLSAEEKLK LDKENQVKSL
PFQHQKENAD NLAEAEGLLK DLFLDVDRAK KLKHPQASEI ESDVSNLHDR WSADCKFYRE
VYEAKKEIGL SPKIGWVQIL NQKQRQVNIE EYGPGMPELE KQIASHNILH KEIEAYGPQL
DGNSTSSPEE LAAIQKQYQN LLENSKWRRH YLGSLYDYMQ GCTKELVYLN EQQEKILKQD
WSDRLTDPSD IRRQYENFKN NSLLAHESEV NKLQDDGDRL IEMKHPASPT IQAHRDAVRN
EWQSFLNLCI CQETHLDNVE DYRKYQDDVD TLLGSLKKLN ASLDPKALSN KTNSEMQLLL
ETEEKTVQQS DQLLADLRKR STKVAPLKLR RTSPTKPTSV ESLCDWETEE ASVTRDEKCT
LKDNSSAENW VLQSSNGQTK TLPGVCFLIP PPDHEAIDKV DRLGVELAEL KKKRAALQSS
LKSQTLEGVR PQRSGLVSST PEDPKVKQLS ASLEQMDKEL AQTEKDVLRR LRTPLDRSSP
SQDLANRLKE QERAAKALQD LEKVRAAAQR EVQPLLAQQP SGPAPSPLPL KLSNAKNKQD
DIAALCDLYT RKANASMELE NQIKKVDGII AGFESRLAKD TGVPDTPNAI QTHTQDLQRM
RKELAGKQDE LQKLSRDLET TEQLCSSLQK GYQEYCPDIR RQEAEVQRLK NRYASVNSQL
LQRENLMQEA ANKNQAFTGT TQSLNSFLNS LPNNRISPGD SLSQVNAKQS SQKRVVEDIR
RKGDDVNRVV DLSNDLQSVL SEYETNSDKY RGTLDSTVGI TDAKRLQASS LADAVQREEK
ALVNRYAEVS AENEQMLNQM GFAKNIIAQN EDKVSQVVVQ QQLQQKSMVE TDNLKSILAE
ETSRRTRVEM DLDNCMKRMM SLKSRRGVER LEEKEVVQYY RDPKLESELV SLRSRVQDES
SRRAITQTEI EVANKKIISV EQELKTIQPK LLTKEVTEIE KDPQLDIEAS RLRDDIRRMK
EEVRLKETDI VHIRTDISIL EKKQPIVKEK VVKKEVVKVE KNPEMLRAVR SFENEISNES
QRCKSLNDEI FNIRSQINTL ERIIPTVQPK IITKEVKKVE QDPELINESK KIRTLIEEER
SMNNNLFAEI SKLQLRYNQV DQTKPKVEIK EIINEIYRVD PETEVELVRL RKELQDSSRR
RADIEKEISI ILVDLQALRS QKPKVELKEV TQEVIKEERS PELIRELSRL NEQVTQLQNT
YNNTQLQLQL LRKERDEWKV EKSKVETKLV TKEVIKYEND PLLEKEANRL NRELREEVQR
RRTMEEMVFD LQNKYIVLER QKPEEKVVVQ ELVRLQKDPR QIMEHEKLSK ELDEEVKSRR
QLELEVQQLM ALVEEKEKLL QQQDERQKKI AVEMELRQVK SRINELETAP PPIEEKIIME
EVLKVERDPK LEAVTSGLRT DLDKQRNEIM RLEREIRNIT LKLEILQRDR SVEKTVYKEV
IRVEKDKMLE GERSRLRDQV NQERNARRDL EDEIRRLTEK LNRLQGARTN TSQEETLLIQ
TKDSLLRDKE KMIRELRTLE SERQHISISF QQQSKLMSER TQMSRQKSIK MDTDVKRLEK
EILDEKDKLN KREITLRELQ ESLRKEDAKN SETQMRETNL STKITILDPE TGKDMSPYDA
YMLGLIDRNQ YIQLQQLECN WEEVTTTGPD GETSVLQDRK SGKQYSIKDA LRDKKVTPME
VQLYREGKIP ISEFALLVAG ETKKQPLLNT PLSAQRSSFT SSSLNVLGGD ENYPISGAID
TTTKSRMSIR SAMTRKLIDP NTGQKLLEAQ AATGGIVDIA NKDRYSVHKA AERGFIDTTS
VNRLLNAQKA FTGVEDPMTK ARLSVGEAVQ KGWMSKDNAM RYMEVQYLTG GLVDPKRAGR
ISVTEAVNQK LIDSAMAKEL QDESCYAKDV VDPITKQKIN YKEAMARCQK DRTTGLLLLP
VASADSSYSS PRSSTYSSYY
//
