ID W5NCD7_LEPOC Unreviewed; 425 AA.
AC W5NCD7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Potassium channel tetramerisation domain containing 12b {ECO:0000313|Ensembl:ENSLOCP00000018296.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000018296.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000018296.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01015680; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NCD7; -.
DR STRING; 7918.ENSLOCP00000018296; -.
DR Ensembl; ENSLOCT00000018328.1; ENSLOCP00000018296.1; ENSLOCG00000014860.1.
DR eggNOG; KOG2723; Eukaryota.
DR GeneTree; ENSGT00940000163673; -.
DR HOGENOM; CLU_057051_1_0_1; -.
DR InParanoid; W5NCD7; -.
DR OMA; LPETGCS; -.
DR Proteomes; UP000018468; Linkage group LG7.
DR Bgee; ENSLOCG00000014860; Expressed in camera-type eye and 11 other cell types or tissues.
DR GO; GO:0043235; C:receptor complex; IBA:GO_Central.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd18367; BTB_POZ_KCTD8-like; 1.
DR CDD; cd22216; H1_KCTD12b; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14499:SF30; POTASSIUM CHANNEL TETRAMERISATION DOMAIN-CONTAINING 12B; 1.
DR PANTHER; PTHR14499; POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 4..107
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 107..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..375
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 47554 MW; 80FA5FCAD45CE032 CRC64;
AFPEIVELNV GGQVYITRSS TLTSVPDSLL WEMFSRKSAR GLARDAKGRF FVDRDGFLFR
YILDYMRDQT LVLPEHFPER GRLQREAEFF NLPELVKLLA PRISKQNSLG DDGCPSDPEE
SSPTADAAAR NLSSLGAAAA AACASLTPGG GAETRRSGFI TIGYRGSYTL GRDSQTDAKF
RRVARIMVCG KTSLAKEVFG DTLNESRDPD RPPERYTSRY YLKFTFLEQA FDRLADAGFH
MVACNSTGTC AFAHDQTDDK IWTSYTEYVF YRELLFLLNS ERRRFFPEPN NREGKGEVGS
EEEGGSRPLP GTGTVTPFTP SSCPSLTTQP YPRPLPAPAL TPPTLPPPPP PPPPTMPPPL
PPSVPPPPPP LPPKDTQDPD VEEEKKLLEE ELQKCIEDFR RIRIPQLFPD RKRHWQSDLL
RKYNA
//
