ID W5NRJ7_SHEEP Unreviewed; 284 AA.
AC W5NRJ7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=F5/8 type C domain-containing protein {ECO:0000259|PROSITE:PS50022};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000000787.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000000787.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000000787.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000000787.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01089804; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5NRJ7; -.
DR SMR; W5NRJ7; -.
DR STRING; 9940.ENSOARP00000000787; -.
DR PaxDb; 9940-ENSOARP00000000787; -.
DR Ensembl; ENSOART00000000819.1; ENSOARP00000000787.1; ENSOARG00000000765.1.
DR eggNOG; KOG1216; Eukaryota.
DR HOGENOM; CLU_979909_0_0_1; -.
DR Proteomes; UP000002356; Chromosome 4.
DR Bgee; ENSOARG00000000765; Expressed in cerebellum and 24 other cell types or tissues.
DR CDD; cd00057; FA58C; 1.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24543; MULTICOPPER OXIDASE-RELATED; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS01286; FA58C_2; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 78..236
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DISULFID 242..254
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 249..267
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 261..276
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 284 AA; 30103 MW; 18C60003CFABA6E4 CRC64;
MERAGDGQVA NSACPARLLH PQDWVLVEGV GESCCSCVPP GENQTVHPMA TPMPAPTPSP
QIGAPLITYL LPPPGDPCYS PLGLAQLPEG SLPASSQHLE HPAWAAILRP DPGAPGWSPM
EHADTQGHTP PHYLQLDLLQ PRNLTGIMVQ GAGSSDWLQV SSDGLHWHSY RDIRPGIQPA
PQLFPENWDG ASTVWMFARM VQARHVRVWP SDGHRQAAPR SDANPGSLLR VELLGCEPAP
LCPGVGHRCA SGECTPRGSL CNGVEDCEDG SDEEGCVPPP AGAG
//
