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Database: UniProt
Entry: W5NW06_SHEEP
LinkDB: W5NW06_SHEEP
Original site: W5NW06_SHEEP 
ID   W5NW06_SHEEP            Unreviewed;      1013 AA.
AC   W5NW06;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   20-DEC-2017, entry version 21.
DE   SubName: Full=Oxoglutarate dehydrogenase like {ECO:0000313|Ensembl:ENSOARP00000002352};
GN   Name=OGDHL {ECO:0000313|Ensembl:ENSOARP00000002352};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000002352, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000002352, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000002352};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000002352}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOARP00000002352}.
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DR   EMBL; AMGL01072016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01072017; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01072018; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSOART00000002403; ENSOARP00000002352; ENSOARG00000002224.
DR   GeneTree; ENSGT00530000063092; -.
DR   OMA; DDSDAYP; -.
DR   OrthoDB; EOG091G025G; -.
DR   Proteomes; UP000002356; Chromosome 25.
DR   ExpressionAtlas; W5NW06; baseline.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR032106; 2-oxogl_dehyd_N.
DR   InterPro; IPR011603; 2oxoglutarate_DH_E1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR031717; KGD_C.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   PANTHER; PTHR23152; PTHR23152; 1.
DR   Pfam; PF16078; 2-oxogl_dehyd_N; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF16870; OxoGdeHyase_C; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   PIRSF; PIRSF000157; Oxoglu_dh_E1; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   TIGRFAMs; TIGR00239; 2oxo_dh_E1; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT   DOMAIN      638    851       Transket_pyr. {ECO:0000259|SMART:
FT                                SM00861}.
FT   COILED      539    559       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1013 AA;  114249 MW;  B99F5F74C10AB2EB CRC64;
     RMNQLRLLPS RLGTQASRLL APHGAQTFSW CSRSSGPPAS FASSGVGGGS SYMEEMYFAW
     LENPQSVHKS WDSFFRKASE EASYSLAQPQ GSVVSESRPA ASSRTETSKL VEDHLAVQSL
     IRAYQIRGHH VAQLDPLGIL DADLDSFVPS DLITTIDKLA FYDLREADLD KEFQLPTTTF
     IGGSENTLSL REIIRRLEGT YCQHIGLEFM FINDVEQCQW IRQKFETPGV MQFSSEEKRT
     LLARLVRSMR FEDFLARKWS SEKRFGLEGC EVMIPALKTI IDKSSEMGIE NVILGMPHRG
     RLNVLANVIR KDLEQIFCQF DPKLEAADEG SGDVKYHLGM YHERINRVTN RNITLSLVAN
     PSHLEAVDPV VQGKTKAEQF YRGDAQGKKV MSILVHGDAA FAGQGVVYET FHLSDLPSYT
     TNGTVHVVVN NQIGFTTDPR MARSSPYPTD VARVVNAPIF HVNADDPEAV IYVCSVAAEW
     RNTFNKDVVV DLVCYRRRGH NEMDEPMFTQ PLMYKQIHRQ APVLKKYADR LIAEGTVTLQ
     EFEEEIAKYD RICEEAYGRS KDKKILHIKH WLDSPWPGFF NMDGEPKSMT CPATGVPEDT
     LTHIGEVASS VPLEDFKIHV GSPRILRGRA DMIRKRTVDW ALAEYMAFGS LLKEGIHVRL
     SGQDVERGTF SHRHHVLHDQ DIDRRTCVPM NHLWPDQAPY TVCNSSLSEY GVLGFELGYA
     MASPSALVLW EAQFGDFHNT AQCIIDQFIS TGQAKWVRHN GIVLLLPHGM EGMGPEHSSA
     RPERFLQMSN DDSDAYPAFT QDFEVRQLYD CNWIVVNWSP YASRCAAHGR QPATVFPFQL
     IIFTPKSLLR HPEAKSSFDQ MVSGTSFQRV IPEDGAAARA PEQVRRLIFC TGQGFYHLGK
     ERGSHHTPGA ALPLILPALP QISPFPFDLI KREAEKYPGA ELVWCQEEHK NMGYYDYISP
     RFTTVLGRAR HIWYVGRDPA AAPATGNRNT HLVSLKKFLD TAFNLQAFEG KTF
//
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