ID W5P6Z4_SHEEP Unreviewed; 336 AA.
AC W5P6Z4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN Name=CCBE1 {ECO:0000313|Ensembl:ENSOARP00000006198.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000006198.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000006198.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000006198.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000006198.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AMGL01067460; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067461; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067466; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01067469; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5P6Z4; -.
DR STRING; 9940.ENSOARP00000006198; -.
DR PaxDb; 9940-ENSOARP00000006198; -.
DR Ensembl; ENSOART00000006292.1; ENSOARP00000006198.1; ENSOARG00000005777.1.
DR eggNOG; KOG1218; Eukaryota.
DR HOGENOM; CLU_062964_0_0_1; -.
DR OMA; SWTYREE; -.
DR Proteomes; UP000002356; Chromosome 23.
DR Bgee; ENSOARG00000005777; Expressed in adrenal cortex and 47 other cell types or tissues.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR PANTHER; PTHR24637; COLLAGEN; 1.
DR PANTHER; PTHR24637:SF428; SCAVENGER RECEPTOR CLASS A MEMBER 3; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 63..104
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 176..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..216
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 336 AA; 36052 MW; ABE7D726423CBFB1 CRC64;
KKCCKGYKFV LGQCIPEDYD VCAEAPCEQQ CTDNFGRVLC TCYPGYRYDR ERHRRREKPY
CLDIDECATS NETLCAHVCV NTLGSYRCEC REGYIQEDDG RTCTKEDKYP NDTGHDEKAE
RAVQAATCCA TCKELHQVKQ TVLQLKQKVA LLPNSAADLG KYITGHKVLA SNAYLPGPPG
LPGGQGPPGS PGPKGSPGFP GIPGPPGQPG PRGSMGPVGP SPDLSHIKQG RRGPVGPPGA
PGRDGSKGER GAPGPRGSPG PPGSFDFLLI VLAEIRNDIT ELQEQVFGRR THSSAEEYPS
PQGFPSYPET LDMGSGDDSP GRTETRASGA PRDFYP
//
