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Database: UniProt
Entry: W5P7E3_SHEEP
LinkDB: W5P7E3_SHEEP
Original site: W5P7E3_SHEEP 
ID   W5P7E3_SHEEP            Unreviewed;       581 AA.
AC   W5P7E3;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSOARP00000006347};
GN   Name=EIF2D {ECO:0000313|Ensembl:ENSOARP00000006347};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000006347, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000006347, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000006347};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000006347}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOARP00000006347}.
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DR   EMBL; AMGL01020019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01020020; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004013618.1; XM_004013569.3.
DR   Ensembl; ENSOART00000006444; ENSOARP00000006347; ENSOARG00000005917.
DR   GeneID; 101117434; -.
DR   KEGG; oas:101117434; -.
DR   CTD; 1939; -.
DR   GeneTree; ENSGT00550000074865; -.
DR   KO; K15027; -.
DR   OMA; REQPYHP; -.
DR   OrthoDB; EOG091G0DTH; -.
DR   Proteomes; UP000002356; Chromosome 12.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IEA:Ensembl.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:Ensembl.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:Ensembl.
DR   GO; GO:0075522; P:IRES-dependent viral translational initiation; IEA:Ensembl.
DR   GO; GO:0032790; P:ribosome disassembly; IEA:Ensembl.
DR   Gene3D; 1.10.245.10; -; 1.
DR   Gene3D; 2.30.130.10; -; 1.
DR   Gene3D; 3.30.780.10; -; 1.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_domain.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF47592; SSF47592; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   PROSITE; PS50890; PUA; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT   DOMAIN       93    173       PUA. {ECO:0000259|PROSITE:PS50890}.
FT   DOMAIN      488    561       SUI1. {ECO:0000259|PROSITE:PS50296}.
SQ   SEQUENCE   581 AA;  64068 MW;  5F5AFACDADC6FAF4 CRC64;
     MFAKAFRVKS NTAIKGSDRR KLRADVAAVF PTLGTDQVSE LVPGKEELNI VKLYAHRGDA
     VTVYVSGGNP ILFELEKNLY PTVYTLWSYP DLLPTFTTWP LVLEKLVGGA DLMLPGLVVP
     PAGLPQVQKG DLCAVALVGN RAPVAVGVAA MSTAEMLASG LKGRGFCVLH SYQDHLWRSG
     DKSSPPSIAP LALDPLDLSE EKGCVKADTA LQGDMRQLTL EEEEEVQQRC EEKSPSEAME
     DPGPGGLHAD PTDSKTLQEQ MDELLQRCFL QALKCCVRKA DLPLLTSTLL GSHMFSCCPE
     GRQLDIKKSS YKKLSKFLQH MQQEQIIQVQ ELSKGVESIV AVDWKHPRIT SFVIPEPSPT
     SQTIQEGSRG QPYHPPDIKP LYCVPASMTL LFQESGHKKG SVLEGSEVRT VVINYAKKND
     LVDADNKNLV KLDPILCDCV LEKDEQHTVM KLPWDSLLSR CLEKLQPAYQ VTFPGQEPIV
     KKGRICPIDI TLAQRASNKK VTMVRNLEAY GLDPRSVAAT LQQRCQASTT VSPAPGLKDS
     LQVQIQGNQI HHLGRLLLEE YRLPRKHIQG LEKAPKPGKK K
//
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