ID W5PA50_SHEEP Unreviewed; 341 AA.
AC W5PA50;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=SGT1 homolog, MIS12 kinetochore complex assembly cochaperone {ECO:0008006|Google:ProtNLM};
GN Name=SUGT1 {ECO:0000313|Ensembl:ENSOARP00000007309.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000007309.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000007309.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000007309.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000007309.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SGT1 family.
CC {ECO:0000256|ARBA:ARBA00008509}.
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DR EMBL; AMGL01013539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PA50; -.
DR SMR; W5PA50; -.
DR STRING; 9940.ENSOARP00000007309; -.
DR PaxDb; 9940-ENSOARP00000007309; -.
DR Ensembl; ENSOART00000007418.1; ENSOARP00000007309.1; ENSOARG00000006823.1.
DR eggNOG; KOG0548; Eukaryota.
DR eggNOG; KOG1309; Eukaryota.
DR HOGENOM; CLU_039532_1_1_1; -.
DR OMA; QRAYCYI; -.
DR Proteomes; UP000002356; Chromosome 10.
DR Bgee; ENSOARG00000006823; Expressed in longissimus thoracis muscle and 55 other cell types or tissues.
DR GO; GO:0051087; F:protein-folding chaperone binding; IEA:InterPro.
DR CDD; cd06489; p23_CS_hSgt1_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR007699; SGS_dom.
DR InterPro; IPR044563; Sgt1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45862; PROTEIN SGT1 HOMOLOG; 1.
DR PANTHER; PTHR45862:SF1; PROTEIN SGT1 HOMOLOG; 1.
DR Pfam; PF04969; CS; 1.
DR Pfam; PF05002; SGS; 1.
DR Pfam; PF00515; TPR_1; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS51048; SGS; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 44..77
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 145..234
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT DOMAIN 252..341
FT /note="SGS"
FT /evidence="ECO:0000259|PROSITE:PS51048"
SQ SEQUENCE 341 AA; 38514 MW; D43E51D422F74317 CRC64;
GAAAAGPAAA ARLFRSFSDA LIEQDPQAAL EELTKALEQK PDDAQYYCQR AYCHILLGNY
SDAVADAKKS LELNPNSSTA LLRKGICEYH EKNYAAALET FTEGQKLNSA DADFIAWIKR
CQEAQNGSQH EVICPNQSAS QRTHQSKIKY DWYQTESQVI ITLMIKNVQK NDVKVEFSEK
ELSALVKLPS GEDYSLKLRL LHPIIPEQST FKVLSTKIEI KMKKPEAVRW EKLEGQGDVP
NPKPFIADVK NLYPSSSHYT RNWDKLVGEI KEEEKNEKLE GDAALNKLFQ QIYSDGSDEV
KRAMNKSFME SGGTVLSTNW SDVGKRKVEI NPPDDMEWKK Y
//
