ID W5PAQ3_SHEEP Unreviewed; 440 AA.
AC W5PAQ3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=B30.2/SPRY domain-containing protein {ECO:0000259|PROSITE:PS50188};
GN Name=TRIM25 {ECO:0000313|Ensembl:ENSOARP00000007514.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000007514.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000007514.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000007514.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000007514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01017237; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01017238; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PAQ3; -.
DR SMR; W5PAQ3; -.
DR STRING; 9940.ENSOARP00000007514; -.
DR PaxDb; 9940-ENSOARP00000007514; -.
DR Ensembl; ENSOART00000007626.1; ENSOARP00000007514.1; ENSOARG00000007011.1.
DR eggNOG; KOG2177; Eukaryota.
DR HOGENOM; CLU_013137_0_2_1; -.
DR OMA; NIQERAY; -.
DR Proteomes; UP000002356; Chromosome 11.
DR Bgee; ENSOARG00000007011; Expressed in omasum and 53 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd13736; SPRY_PRY_TRIM25; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR042753; TRIM25_SPRY_PRY.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF40; E3 UBIQUITIN_ISG15 LIGASE TRIM25; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 249..440
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 150..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 19..107
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 150..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 49575 MW; CADA8B27EE4D7B30 CRC64;
SFSLQNKLRQ KLTVMYGQIN GASRALEDVR ARQQEVQEAA HRKMDQLRQE YLEMKALIDA
SEASATRKIK EEEKRVTSKF DSIYQIILKK RSEIQTLKEE VELALTKGDE FEFLEKATKL
QGITTKPVFV PKVELNHELI KEVYQSTSDL KNELKRSLRQ PQDKKLEELT VPGPGDAGGS
CAPHTPKPHR PVKKVAKEEK KPKKPASALL NKPVTFGSSE HLVNLKQPGQ EGAAKAPAVP
PTSASLNAKV LENFLSKSRP ELLEYVVKVV LDYNTAHSKV ALSENYTVAS VAETSLNYRP
HPQRFTYCSQ VLGLHCYKKG IHYWEVELQK NNFCGVGICY GSMERQGPES RLGRNSASWC
VEWFNTKISA WHNNVEKTLP STKATRVGVL LNCDHGFVLF FAAADKVHLL YKYKVDFTEA
VYPAFWLFST GAMLSICSSK
//
