ID W5PK78_SHEEP Unreviewed; 799 AA.
AC W5PK78;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=von Willebrand factor A domain-containing protein 5A {ECO:0008006|Google:ProtNLM};
GN Name=VWA5A {ECO:0000313|Ensembl:ENSOARP00000010849.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000010849.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000010849.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000010849.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000010849.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01061225; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01061226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01061227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PK78; -.
DR SMR; W5PK78; -.
DR STRING; 9940.ENSOARP00000010849; -.
DR PaxDb; 9940-ENSOARP00000010849; -.
DR Ensembl; ENSOART00000011007.1; ENSOARP00000010849.1; ENSOARG00000010118.1.
DR eggNOG; ENOG502QRPK; Eukaryota.
DR OMA; CQELMRR; -.
DR Proteomes; UP000002356; Chromosome 21.
DR Bgee; ENSOARG00000010118; Expressed in adrenal medulla and 51 other cell types or tissues.
DR ExpressionAtlas; W5PK78; baseline.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR013694; VIT.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR45737; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR PANTHER; PTHR45737:SF8; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR Pfam; PF08487; VIT; 1.
DR Pfam; PF13768; VWA_3; 1.
DR SMART; SM00609; VIT; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51468; VIT; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 1..131
FT /note="VIT"
FT /evidence="ECO:0000259|PROSITE:PS51468"
FT DOMAIN 281..462
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 799 AA; 88046 MW; 73F11B0D245BEC77 CRC64;
MVYPGGLLTP QEKSVPLKSI SVTLSICEFV AGVSATLNYK NEEEVPLEAF FIFPMDEDSA
VYSFEAMVDG KNVKAELQDK MTAHTNYENA IIRGHQAFLL EEDMCSRDVF CCNVGNLLPG
SQAELTLKYV QELPLEADGA LRYVLPAVLN PRYQLSGCSE DSCLNMKTPV VSLEDLPYTI
SMVATISSQH GIDRIQSNCS LSPIEYFGDN KTSAQVSLAD GHKFDRDVEF LIYYRAVHTP
SVVVEMGEAT TKSDGVLGDP AAMVTFYPNI PEAQASIPCG EFIFLMDCSG SMQSPISKQR
RSQLRIDVAK ETLILLLKSL PLGCYFNIYE FGSTYEAFFP NSVKYAQSTV EEALQRVKLM
RANLGGTEIL TPLQHIYKQP SVPGHPLQVF VFTDGEVTDT FTVVREVKSH CLRHRCFSFG
IGEGVSTSLV KGIARVSRGT SEFITGKERM QAKALRALKR SLQPVVDDVS LSWDLPDGLS
AKMLSPEQTV LFRGQRLILY AQLTGTMPPA EATGEVCLKY TLQGESLENK VTFSLQPKLD
ANLTIHRLAA KSFLQTKDMG LRETPAGDKK DVLKVSMECG VISSHTAFIA VNKDFSKPIQ
GPLAPRDVPR PMLLHAAPVM QSMSLQSGTK LLKGIRSYSL KKPLVMKLTM QKRSLSCVKS
SRRQKACLEK PKSRASAKKT NAETHGPVVE DNRLAQLISL QKADGSWDLN EGLALVLGMK
LEDIQAALPD KDVNSSSWAT VLAVLWLHDN AKDMDCEWEL LERKAVAWIH IHAGSVRHEL
VKAAIAFVKS SVDPAIFGP
//
