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Database: UniProt
Entry: W5PNA5_SHEEP
LinkDB: W5PNA5_SHEEP
Original site: W5PNA5_SHEEP 
ID   W5PNA5_SHEEP            Unreviewed;      1768 AA.
AC   W5PNA5;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   25-OCT-2017, entry version 31.
DE   SubName: Full=Kinesin family member 13A {ECO:0000313|Ensembl:ENSOARP00000011931};
GN   Name=KIF13A {ECO:0000313|Ensembl:ENSOARP00000011931};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000011931, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000011931, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000011931};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000011931}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00283, ECO:0000256|SAAS:SAAS00583243}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOARP00000011931}.
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DR   EMBL; AMGL01059458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01059459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01059460; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01059461; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSOART00000012105; ENSOARP00000011931; ENSOARG00000011127.
DR   GeneTree; ENSGT00890000139327; -.
DR   OMA; KLDYHTP; -.
DR   OrthoDB; EOG091G0091; -.
DR   Proteomes; UP000002356; Chromosome 20.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0010008; C:endosome membrane; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0035459; P:cargo loading into vesicle; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; IEA:Ensembl.
DR   GO; GO:0008333; P:endosome to lysosome transport; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0032438; P:melanosome organization; IEA:Ensembl.
DR   GO; GO:0072383; P:plus-end-directed vesicle transport along microtubule; IEA:InterPro.
DR   CDD; cd00060; FHA; 1.
DR   Gene3D; 2.60.40.150; -; 1.
DR   Gene3D; 3.40.850.10; -; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR032923; KIF13A.
DR   InterPro; IPR022164; Kinesin-like.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR   InterPro; IPR032405; Kinesin_assoc.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR008984; SMAD_FHA_domain.
DR   PANTHER; PTHR24115; PTHR24115; 1.
DR   PANTHER; PTHR24115:SF458; PTHR24115:SF458; 1.
DR   Pfam; PF12473; DUF3694; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF12423; KIF1B; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   Pfam; PF16183; Kinesin_assoc; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|SAAS:SAAS00875240}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283,
KW   ECO:0000256|SAAS:SAAS00874078};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT   DOMAIN        1    323       Kinesin motor. {ECO:0000259|PROSITE:
FT                                PS50067}.
FT   NP_BIND      73     80       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00283}.
FT   COILED      335    358       {ECO:0000256|SAM:Coils}.
FT   COILED      578    605       {ECO:0000256|SAM:Coils}.
FT   COILED     1077   1104       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1768 AA;  197885 MW;  891AB99A9663CF17 CRC64;
     MEGNQTVLHP PPSNTKQGER KPPKVFAFDY CFWSMDESNT TKYAGQEVVF KCLGEGILEK
     AFQGYNACIF AYGQTGSGKS FSMMGNAEQR GLIPRLCCAL FQRISLEQNE SQTFKVEVSY
     MEIYNEKVRD LLDPKGSRQS LKVREHKVLG PYVDGLSQLA VTSFEDIESL MSEGNKSRTV
     AATNMNEESS RSHAVFNIVI TQTLYDLQSG NSGEKVSKVS LVDLAGSERV SKTGAAGERL
     KEGSNINKSL TTLGLVISSL ADQAAGKGKN KFVPYRDSVL TWLLKDNLGG NSQTSMIATI
     SPAADNYEET LSTLRYADRA KRIVNHAVVN EDPNAKVIRE LREEVEKLRE QLSQAEAMKA
     PELKEKLEES EKLIKELTVT WEEKLRKTEE IAQERQRQLE SMGISLETSG IKVGDDKCYL
     VNLNADPALN ELLVYYLKDH TRVGADTSQD IQLFGIGIQP EHCEIDIGSD GEVSLTPKEN
     ARSCVNGTLV CSPTQLWHGD RILWGNNHFF RINLPKRKRR DWLKDFEKET GPPEHDLDAA
     SEASSEPDYN YEFAQMEVIM KTLNSNDPVQ NVVQVLEKQY LEEKRSALEE QRLMYERELE
     QLRQQLSPER QPQISGPDRL AYSSQTAQQK VTQWAEERDE LFRQSLAKLR EQLVKANTLV
     REANFLAEEM SKLTDYQVTL QIPAANLSAN RKRGAIVSEP AIQVRRKGKS TQVWTIEKLE
     NKLIDMRDLY QEWKEKIPEA KRLCGKRGDP FYEAQENHNL IGVANVFLEC LFCDVKLQYA
     VPIISQQGEV AGRLHVEVMR VTGAVPERMV EDDSSENSSE SGSLEVVDST GEIIHRVKKL
     TCRVKIKEAT GLPLNLSNFV FCQYTFWDQC ESTVAAPVVD PEVPSPQSKD AQYTVTFSHC
     EDYVVNVTEE FLEFISDGAL AIEVWGHRCT GNGSSIWEVD SLHAKTRTLH DRWNEVTRRI
     EMWISILELN ELGEYAAVEL HQAKDVNTGG VFQLRQGHSR RVQVTVKPVQ HSGTLPLMVE
     AILSISIGCI TARSTKLQRG LDSYQRDDED GDDMDSYQEE DLNCVRERWS DALIKRREYL
     DEQIKKVSNK KEKTEDDVER EARLVEQWVG LTEERNAVLV PAPGSGIPGA PADWIPPPGM
     ETHIPVLFLD LNADDLSANE QLVGPHASGV NSILPKEHGS QFFYLPIIKH SDEEVSATAS
     WDSSVHDSVH LNRVTPQNER IYLIVKTTVQ LSHPAAMELV LRKRIAANIY NKQSFTQSLK
     RRISLKNIFY SCGVTYEIVS NIPKATEEIE DRETLALMAA RSENEGTSDG ETYIEKYTRG
     VLQVENILSL ERLRQAVTVK EALSTKARHL RRSLSTPNVH NVSSSRPDLS GFDDDDKGWP
     ENQLDMSDYS PSYQDVSCYG TLPRDSPRRS KEGCTSENPH ALTVSPFKAF SPQPPKFFKP
     LMPVKEERKK RIALEARPLL SQESMSPSQA HNPGCIVPSG SNGSSMPVEL NSKREKKIDS
     EEEENDLEGL SRKLISSQPY VPVEFADFSV YNASLENREW FSSKGDLTNS KVLEKEVSRS
     PTTSSITSGY FSHSASNATL SDMVVPSSDS SDQLALPMKD TDSSEHPGPS LVQDFRPSSN
     KELTELERGL GKDKMTVVPL KENSALAKGS PLSPSIPEKN SRTPCRTSSC SEQDACSSKN
     GQQAREFCPR EVTVEHTTSI LEDHSFTEFM GVSDGKDFDG LTDSSAGELS SRRNLPNTAD
     SRSISHGPQD SGQLCSSAEN DQGSTAAR
//
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