ID W5PNP0_SHEEP Unreviewed; 768 AA.
AC W5PNP0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Cyclin-like domain-containing protein {ECO:0000259|SMART:SM00385};
GN Name=CCNT2 {ECO:0000313|Ensembl:ENSOARP00000012066.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000012066.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000012066.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000012066.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000012066.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cyclin family.
CC {ECO:0000256|RuleBase:RU000383}.
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DR EMBL; AMGL01054178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PNP0; -.
DR SMR; W5PNP0; -.
DR STRING; 9940.ENSOARP00000012066; -.
DR PaxDb; 9940-ENSOARP00000012066; -.
DR Ensembl; ENSOART00000012242.1; ENSOARP00000012066.1; ENSOARG00000011259.1.
DR eggNOG; KOG0834; Eukaryota.
DR HOGENOM; CLU_012994_1_0_1; -.
DR OMA; SCSVKQY; -.
DR Proteomes; UP000002356; Chromosome 2.
DR Bgee; ENSOARG00000011259; Expressed in thymus and 54 other cell types or tissues.
DR ExpressionAtlas; W5PNP0; baseline and differential.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20596; CYCLIN_CCNT2_rpt1; 1.
DR CDD; cd20598; CYCLIN_CCNT2_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR047321; CYCLIN_CCNT2_rpt1.
DR InterPro; IPR047322; CYCLIN_CCNT2_rpt2.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR PANTHER; PTHR10026:SF43; CYCLIN-T2; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR Pfam; PF21797; CycT2-like_C; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cyclin {ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 144..243
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 256..344
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 72..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..665
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..680
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..725
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..759
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 768 AA; 85108 MW; 320A5E049A5968B7 CRC64;
MHCADLFLPA DPHLWAPPND KGRGALWSRA RERGWRQERE SKRLDEPIYR SPRTRTHGDG
GEKRRCLVYG ERSGAGSRGL GGESASPEGR GVGEGAGGGG SVMASGRGAS SRWFFTREQL
ENTPSRRCGV EADKELSYRQ QAANLIQEMG QRLNVSQLTI NTAIVYMHRF YMHHSFTKFS
RYMISPTALF LAAKVEEQAR KLEHVIKVAH ACLHPLEPLL DTKCDTYLQQ TQELVLLETI
MLQTLGFEIT IEHPHTDVVK CTQLVRASKD LAQTSYFMAT NSLHLTTFCL QYKPTVIACV
CIHLACKWSN WEIPVSTDGK HWWEYVDPTV TLELLDELTH EFLQILEKTP SRLKKIRYWR
ANQAAGKPKV DGQVSETPLL GSSLVQNSML VDSVTGVPTK PSFQKPSTSA FPAPVPLNSG
NISVQDSHAS DNLSMLATGM PSTSYGLSSH QEWPQHQESA RTEQIYSQKQ ETSLSGSQYN
INFKQGPSAS LHSGLHHRPD KISDHSSVKQ DYTHKAGSSK HHGPISATPG VIPQKMSLDK
YREKRKLESL DLDARDHYIA AQVEQQHKHV QSQAASSSSV TSPIKMKIPI TNAEKPEKYM
AEKKEKSGSL KLRIPIPPTD KSVSKEELKM KIKVSSSERH SSSDEGSGKS KHSSPHISRD
HKEKHKEHPS NRHHPSSHKH SHSYSGSSSG GSKHSADGIP PTVLRSPVGL SSDGISSSSS
SSRKKLHIND ASHNHHSKMS KSSKSSGGLR TSQHPRETGQ EASGDQRS
//
