ID W5PP19_SHEEP Unreviewed; 606 AA.
AC W5PP19;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Tripartite motif containing 80 {ECO:0008006|Google:ProtNLM};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000012195.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000012195.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000012195.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000012195.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01019356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PP19; -.
DR SMR; W5PP19; -.
DR STRING; 9940.ENSOARP00000012195; -.
DR PaxDb; 9940-ENSOARP00000012195; -.
DR Ensembl; ENSOART00000012371.1; ENSOARP00000012195.1; ENSOARG00000011379.1.
DR eggNOG; KOG2177; Eukaryota.
DR eggNOG; KOG2226; Eukaryota.
DR HOGENOM; CLU_013137_0_2_1; -.
DR OMA; MVACFTQ; -.
DR Proteomes; UP000002356; Chromosome 11.
DR Bgee; ENSOARG00000011379; Expressed in testis and 27 other cell types or tissues.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19802; Bbox1_TRIM8-like; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF34; TRIPARTITE MOTIF-CONTAINING 80; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 62..106
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 197..238
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 416..604
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 606 AA; 68189 MW; 361E29E86CF54162 CRC64;
TQQQPKGKGS KPLALLDMQR VSRPVQDQAP ALQPTAKLSG APQGQFLMNN SSLCTLEEQV
LCPVCLEVFR NPVTTACGHN FCMSCLQGFW DYQATMGEPL YCPQCRESFP TRPRLCKNVI
LEEMVTCFTQ AKGQTLGSSR SLAGPRDVPC DFCAPEKLKS VKSCLQCMAS LCEKHLRSHL
EDQVFQGHQL LEPVWDLKSR LCRKHRKLRR LYCRTEGCCV CGACLSLEEH KNHDTIPLEE
ERARKEVEVR KVQANVENQM LIITSDSQKH RGQVAFLSKL IQTTRDEVNA CFSEIIQEIK
QMQVKVLDFV EKEEATALGK LGGSIQQSHN RLLKLEGDSI WLRSLLANRS DQQFLQELPR
LKHFPACMEP LMGTNCEEKQ SFLQLPETLA ELRTRLVDMG LSFINQLLLK GIKMNSYEVL
PPDVDRKILL KCYCNLNFDP TTASEELFLF KETHSVLNLG ILLEPFAAGG PPPPRGLAEG
RHYWEADVSN SWVCLGVTYR RSPPLGGRPR RSIVYLLGRN PYSWCLEWDS LKFSVWHNNT
QTVLHGGYNR TGVMLDCAAG CLSFYGVAGG VSLLYRFLAS FLEPLYPAVM VSSGASVTLK
QHPSEA
//
