ID W5PYI7_SHEEP Unreviewed; 334 AA.
AC W5PYI7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Phospholipid/glycerol acyltransferase domain-containing protein {ECO:0000259|Pfam:PF01553};
GN Name=TMEM68 {ECO:0000313|Ensembl:ENSOARP00000015521.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000015521.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000015521.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000015521.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000015521.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01111047; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012039103.1; XM_012183713.2.
DR RefSeq; XP_014953239.1; XM_015097753.1.
DR RefSeq; XP_014953240.1; XM_015097754.1.
DR RefSeq; XP_014953241.1; XM_015097755.1.
DR RefSeq; XP_014953242.1; XM_015097756.1.
DR RefSeq; XP_014953243.1; XM_015097757.1.
DR RefSeq; XP_014953244.1; XM_015097758.1.
DR RefSeq; XP_014953246.1; XM_015097760.1.
DR RefSeq; XP_014953247.1; XM_015097761.1.
DR AlphaFoldDB; W5PYI7; -.
DR STRING; 9940.ENSOARP00000015521; -.
DR PaxDb; 9940-ENSOARP00000015521; -.
DR Ensembl; ENSOART00000015748.1; ENSOARP00000015521.1; ENSOARG00000014466.1.
DR GeneID; 101114876; -.
DR KEGG; oas:101114876; -.
DR CTD; 137695; -.
DR eggNOG; KOG4321; Eukaryota.
DR HOGENOM; CLU_056812_1_0_1; -.
DR OMA; CKVFSIT; -.
DR OrthoDB; 4577176at2759; -.
DR Proteomes; UP000002356; Chromosome 9.
DR Bgee; ENSOARG00000014466; Expressed in spleen and 53 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR CDD; cd07987; LPLAT_MGAT-like; 1.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR22753; TRANSMEMBRANE PROTEIN 68; 1.
DR PANTHER; PTHR22753:SF14; TRANSMEMBRANE PROTEIN 68; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..234
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF01553"
SQ SEQUENCE 334 AA; 38501 MW; 8AEEB294659E77C7 CRC64;
MTNKNQSCGM GQDSMPSMTC LIHVLEAWLG VEHLEDYWNF ANYLLWVFTP LLLLILPYFT
IFLLYLTIIF LHIYKRKNVL KEAYSHNLWD GARKTVATLW DGHAAVWHGY EVHGMEKIPE
EGPALIIFYH GAIPIDFYYF MAKIFIHKGR TCRVVADHFV FKIPGFSLLL DVFCAIHGPR
EKCVEILQSG HLLAISPGGV REALMSDETY NIVWGNRKGF AQVAIDAKVP IIPMFTQNIR
EGFRSLGGTR LFRWLYEKFR YPFAPMYGGF PVKLRTYLGD PIPYDPKITA EELAEKTKDA
VQALIDKHQR IPGNIMSALL ERFHNKEKIN QKTL
//
