GenomeNet

Database: UniProt
Entry: W5PYR4_SHEEP
LinkDB: W5PYR4_SHEEP
Original site: W5PYR4_SHEEP 
ID   W5PYR4_SHEEP            Unreviewed;       723 AA.
AC   W5PYR4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   30-AUG-2017, entry version 19.
DE   SubName: Full=Potassium voltage-gated channel subfamily B member 2 {ECO:0000313|Ensembl:ENSOARP00000015599};
GN   Name=KCNB2 {ECO:0000313|Ensembl:ENSOARP00000015599};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000015599, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000015599, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000015599};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000015599}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOARP00000015599}.
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DR   EMBL; AMGL01111522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSOART00000015830; ENSOARP00000015599; ENSOARG00000014544.
DR   GeneTree; ENSGT00760000118981; -.
DR   OMA; KMENHLF; -.
DR   OrthoDB; EOG091G0FP3; -.
DR   Proteomes; UP000002356; Chromosome 9.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003973; K_chnl_volt-dep_Kv2.
DR   InterPro; IPR005826; K_chnl_volt-dep_Kv2.2.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03521; Kv2channel; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01515; KV22CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01495; SHABCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM     45     65       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    147    168       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    180    197       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    209    229       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        5    239       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   723 AA;  80370 MW;  859A830CE11605ED CRC64;
     SFLFQILAIV SILFIVLSTI ALSLNTLPEL QEMDEFGQPN DNPQLAHVEA VCIAWFTMEY
     LLRFLSSPNK WKFFKGPLNV IDLLAILPYY VTIFLTESNK SVLQFQNVRR VVQIFRIMRI
     LRILKLARHS TGLQSLGFTL RRSYNELGLL ILFLAMGIMI FSSLVFFAEK DEDATKFTSI
     PASFWWATIT MTTVGYGDIY PKTLLGKIVG GLCCIAGVLV IALPIPIIVN NFSEFYKEQK
     RQEKAIKRRE ALERAKRNGS IVSMNLKDAF ARSMELIDVA VEKTGESANT KGSTDDNHLS
     PSRWKWARKA LSETSSNKSY ENKYQEVSQK DSHEQLNNTS SSSPQHLSAQ KLEMLYNEIT
     KTQPHSHPNP DGQEQAERPS AYEEEIEMEE VVCPQEQLAV AQTEGVMDMK STSSIDSFTS
     CATDFTETER SPLPPPSASH LQMKFPPDLA GIEEHQRARH PPFLTLIREK GPMAREATPE
     YAPIDVTVNL DAAGGPQGGP HGPLPTDSAS ESPKSSLKGS NPLKSRSLKV NFKDSRGGAP
     PTPPSTARPL PVTAADFPLT APQLISTILL EETPSQGDRP LLGAEVHCQG PSKGLTPRFP
     KQKLFTFSTR ERRSFTEIDT GEDDDFLELQ GTRRPDKQAD SSPNCLTDKP SDGRDPLREE
     ACVGSSSAQD TSHNCRQDIY HGVAEVKKDN SQEGCKMENH LFAPEIHSNP GDTGYCPTRE
     TSM
//
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