GenomeNet

Database: UniProt
Entry: W5Q5F2_SHEEP
LinkDB: W5Q5F2_SHEEP
Original site: W5Q5F2_SHEEP 
ID   W5Q5F2_SHEEP            Unreviewed;       690 AA.
AC   W5Q5F2;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   25-OCT-2017, entry version 32.
DE   SubName: Full=Cyclic nucleotide gated channel alpha 1 {ECO:0000313|Ensembl:ENSOARP00000017942};
GN   Name=CNGA1 {ECO:0000313|Ensembl:ENSOARP00000017942};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000017942, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000017942, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000017942};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000017942}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOARP00000017942}.
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DR   EMBL; AMGL01098471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSOART00000018193; ENSOARP00000017942; ENSOARG00000016704.
DR   GeneTree; ENSGT00900000140801; -.
DR   OMA; CMYFAIS; -.
DR   OrthoDB; EOG091G03EW; -.
DR   Proteomes; UP000002356; Chromosome 6.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042622; C:photoreceptor outer segment membrane; IEA:Ensembl.
DR   GO; GO:0005221; F:intracellular cyclic nucleotide activated cation channel activity; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR032406; CLZ_dom.
DR   InterPro; IPR032945; CNGA1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR10217:SF387; PTHR10217:SF387; 1.
DR   Pfam; PF16526; CLZ; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00502630, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637}.
FT   TRANSMEM    301    319       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    373    395       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      477    583       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
SQ   SEQUENCE   690 AA;  79854 MW;  4387B47F9B5A98E1 CRC64;
     MKKMIINTWR SFVNIPNVVG PDVEQEIRRM ENGACSSFSD DDDDSASIFE ESESENPHAR
     DSFRSDTHGS GQPSQREQYL PGAIALFNVN NSSNKEQEPK EKKKKKKEKK SKPDDKNENK
     KDPEKKKKKE KDKDKKKKEE KGKDKKEEEK KEVVVIDPSG NTYYNWLFCI TLPVMYNWTM
     IIARACFDEL QSDYLEYWFV FDYLSDIVYL LDMFVRTRTG YLEQGLLVRE ERKLIEKYKS
     TFQFKLDVLS VIPTDLLYIK FGWNYPEIRL NRLLRISRMF EFFQRTETRT NYPNIFRISN
     LVMYIIIIIH WNACVYFSIS KAIGFGNDTW VYPDVNDPDF GRLARKYVYS LYWSTLTLTT
     IGETPPPVRD SEYFFVVADF LIGVLIFATI VGNIGSMISN MNAARAEFQA RIDAIKQYMH
     FRNVSKDMEK RVIKWFDYLW TNKKTVDERE VLKYLPDKLR AEIAINVHLD TLKKVRIFAD
     CEAGLLVELV LKLQPQVYSP GDYICKKGDI GREMYIIKEG KLAVVADDGI TQFVVLSDGS
     YFGEISILNI KGSKAGNRRT ANIKSIGYSD LFCLSKDDLM EALTEYPDAK GMLEEKGKQI
     LMKDGLLDIN IANAGSDPKD LEEKVTRMES SVDLLQTRFA RILAEYESMQ QKLKQRLTKV
     EKFLKPLIDT EFSAIEGSGT ESGPTDSTQD
//
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