ID W5Q9K0_SHEEP Unreviewed; 682 AA.
AC W5Q9K0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Outer dynein arm-docking complex subunit 4 {ECO:0000256|ARBA:ARBA00034139};
DE AltName: Full=Tetratricopeptide repeat protein 25 {ECO:0000256|ARBA:ARBA00034143};
GN Name=ODAD4 {ECO:0000313|Ensembl:ENSOARP00000019392.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000019392.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000019392.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000019392.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000019392.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
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DR EMBL; AMGL01018659; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5Q9K0; -.
DR SMR; W5Q9K0; -.
DR STRING; 9940.ENSOARP00000019392; -.
DR PaxDb; 9940-ENSOARP00000019392; -.
DR Ensembl; ENSOART00000019662.1; ENSOARP00000019392.1; ENSOARG00000018067.1.
DR eggNOG; KOG1124; Eukaryota.
DR HOGENOM; CLU_023648_2_1_1; -.
DR OMA; NKEDLCF; -.
DR Proteomes; UP000002356; Chromosome 11.
DR Bgee; ENSOARG00000018067; Expressed in fallopian tube and 20 other cell types or tissues.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR040111; ODAD4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR23040:SF1; OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR23040; UNCHARACTERIZED; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 363..396
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 157..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 446..473
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 513..551
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 561..588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..682
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 78249 MW; 5BC0A980891CAEA6 CRC64;
MADPENEVLR STFPSYMAEG ERLYLCGEFA KAAHSFSNAL HLQSGDKNCL VARSKCFLKM
GELEKSLEDA EASLQGDPTF CKGILQKAET LYTMGDFEFA LVFYHRGYKL RPDREFKIGI
QKAQEAINNS VGSPSSIKLE NKGDLSFLSK QAESMRAQQK PHPVRQLVHH PKRESKRKGS
LKSEKIVRQL LGELYVDKEY LEKLLLDEDL IRGTIKHGLT VEDLIMTGIN YLDTRSDFWR
QQKPIYARER DRKLMQERWL RDRKRRPSQT ARYILKSLED IDMLLTSGSA EGSLQKAEKA
EKVLKKVLEW NKEEVPNKDE LVGNLYSCIG NAQIELGQMV AALQSHRKDL EIAKEYDLPD
AKSRALDNIG RVFARVGKFQ QAIDTWEEKI PLAKTTLEKT WLFHEIGRCY LELDQAWEAQ
SYGEKSQQCA EEEGDMEWQL NASVLVAQAQ VKLRDFESAV NNFEKALERA KLVHNNEAQQ
AIINALDDAN KGIIEELKKT NYREILKEKK EKENATMLDQ TRTAKEKETR KTKDEPEKVM
KQWEQERQPE GVLSKETLGV TARQPEHRQR EDPEKASWRK ELGAKERGPG DTAKGQFGEP
GRTAQNREET REIYRRPSEL DQNLSDESSP RESEGLEKSL SKTDGGELEA LGKTESGETK
EMEITENSEK IEKDEKEDEP TE
//
