ID W5QAL4_SHEEP Unreviewed; 473 AA.
AC W5QAL4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=LRRCT domain-containing protein {ECO:0000259|SMART:SM00082};
GN Name=RTN4R {ECO:0000313|Ensembl:ENSOARP00000019759.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000019759.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000019759.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000019759.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000019759.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01040501; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5QAL4; -.
DR SMR; W5QAL4; -.
DR STRING; 9940.ENSOARP00000019759; -.
DR PaxDb; 9940-ENSOARP00000019759; -.
DR Ensembl; ENSOART00000020032.1; ENSOARP00000019759.1; ENSOARG00000018410.1.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_000288_18_6_1; -.
DR OMA; HPHAFHD; -.
DR Proteomes; UP000002356; Chromosome 17.
DR Bgee; ENSOARG00000018410; Expressed in cerebellum and 45 other cell types or tissues.
DR GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR GO; GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24366; IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS; 1.
DR PANTHER; PTHR24366:SF70; RETICULON 4 RECEPTOR; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..473
FT /note="LRRCT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004870079"
FT DOMAIN 260..310
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 313..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 50141 MW; F4CA2AFE956B8A0C CRC64;
MGTASSGGSQ LLAWVLWLQA WRVAAPCPGA CVCYSEPKVT TSCPQQGLQA VPADIPAASQ
RVFLHGNRIA YVPAAGFRAC RNLTILWLHS NALAHIDAAA FSGLALLEQL DLSDNAQLRA
VDPATFRGLG RLHTLHLDRC GLRELGPGLF RGLAALQYLY LQDNGLQALP DDAFSDLGNL
THLFLHGNRI PSVPERAFRG LHSLDRLLLH QNRVARVHPH AFRDLGRLMT LYLFANNLSA
LPAEALAPLR SLQYLRLNDN PWVCDCRARP LWAWLQQFRG SSSELPCSLP ARLAGRDLKR
LAAPDLEGCA VASRPAPPIW TGGPADEEPL GLPKCCQPDA VDKASVLEAG RPASAGNALK
GRVPPGDSAP GNRSGPRHIN DSPFGTLPGS AEPPLTAVQP EGSQPPGSPT TGPRRRPGCS
RKNRTRSQCR LGQAGGGGGG SGGVEGSGSP PGLACGLVPL ALTLVLWTVL GRC
//
