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Database: UniProt
Entry: W5QDS2_SHEEP
LinkDB: W5QDS2_SHEEP
Original site: W5QDS2_SHEEP 
ID   W5QDS2_SHEEP            Unreviewed;       629 AA.
AC   W5QDS2;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-SEP-2017, entry version 28.
DE   SubName: Full=Potassium voltage-gated channel subfamily C member 4 {ECO:0000313|Ensembl:ENSOARP00000020870};
GN   Name=KCNC4 {ECO:0000313|Ensembl:ENSOARP00000020870};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000020870, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000020870, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000020870};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000020870}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOARP00000020870}.
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DR   EMBL; AMGL01004093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01004094; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSOART00000021158; ENSOARP00000020870; ENSOARG00000019428.
DR   GeneTree; ENSGT00760000118846; -.
DR   OMA; YCKSEET; -.
DR   OrthoDB; EOG091G0EJL; -.
DR   Proteomes; UP000002356; Chromosome 1.
DR   GO; GO:0043679; C:axon terminus; IEA:Ensembl.
DR   GO; GO:0031594; C:neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003974; K_chnl_volt-dep_Kv3.
DR   InterPro; IPR005405; K_chnl_volt-dep_Kv3.4.
DR   InterPro; IPR021105; K_chnl_volt-dep_Kv3_ID.
DR   InterPro; IPR011333; SKP1/BTB/POZ.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF11404; Potassium_chann; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01583; KV34CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01498; SHAWCHANNEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00091688}.
FT   TRANSMEM    283    304       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    316    334       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    384    405       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    426    443       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    455    484       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       36    152       BTB. {ECO:0000259|SMART:SM00225}.
SQ   SEQUENCE   629 AA;  68843 MW;  8F9C98319E03B1D0 CRC64;
     MISSVCVSSY RGRKSGNKPP SKTCLKEEMA KGEASEKIII NVGGTRHETY RSTLRTLPGT
     RLARLAHXLA APDGGGRPES DGGGAGSSCG GGCEFFFDRH PGVFAYVLNY YRTGKLHCPA
     DVCGPLFEEE LTFWGIDETD VEPCCWMTYR QHRDAEEALD IFESPDGGGG GGSLGPGEGA
     GRQSPWRPAR AEIGQHGTGS LQGQGRSGGW ARAWSHLGSR SNLSSEAARV VAFASLFFIL
     VSITTFCLET HEAFNIDRNV TEIHRVGNTT SVRFRREVET EPILTYIEGV CVLWFTLEFL
     VRIVCCPDTL DFVKNLLNII DFVAILPFYL EVGLSGLSSK AARDVLGFLR VVRFVRILRI
     FKLTRHFVGL RVLGHTLRAS TNEFLLLIIF LALGVLIFAT MIYYAERIGA RPSDPRGNDH
     TDFKNIPIGF WWAVVTMTTL GYGDMYPKTW SGMLVGALCA LAGVLTIAMP VPVIVNNFGM
     YYSLAMAKQK LPKKRKKHVP RPPQLESPIY CKSQETSPRD STYSDASPPA PEEGVVERKR
     ADSKQNGDAN AVLSDEEGAG LTQPLASAPT PEERRALRRS GTRDRNKKAA ACFLLSAGDY
     ACADGSVRKE TCQDALSSNY AQAEVLTLS
//
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