ID W5QHJ0_SHEEP Unreviewed; 602 AA.
AC W5QHJ0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
GN Name=KLHL24 {ECO:0000313|Ensembl:ENSOARP00000022190.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000022190.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000022190.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000022190.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000022190.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01009307; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01009308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5QHJ0; -.
DR SMR; W5QHJ0; -.
DR STRING; 9940.ENSOARP00000022190; -.
DR PaxDb; 9940-ENSOARP00000022190; -.
DR Ensembl; ENSOART00000022495.1; ENSOARP00000022190.1; ENSOARG00000020648.1.
DR eggNOG; KOG1721; Eukaryota.
DR eggNOG; KOG4441; Eukaryota.
DR HOGENOM; CLU_004253_14_2_1; -.
DR OMA; QTFNKQE; -.
DR Proteomes; UP000002356; Chromosome 1.
DR Bgee; ENSOARG00000020648; Expressed in skeletal muscle tissue of biceps brachii and 53 other cell types or tissues.
DR CDD; cd18463; BACK_KLHL24; 1.
DR CDD; cd18253; BTB_POZ_KLHL24_KRIP6; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR030596; BTB_POZ_KLHL24.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR047071; KLHL24_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF215; KELCH-LIKE PROTEIN 24; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 66..133
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 602 AA; 68563 MW; AEEBEFFE37FAD2B8 CRC64;
MVLILGRRLN REDLGVRDSP ATKRKVFEMD PKSLTGREFF DFSSGSSHAE NILQIFNEFR
DSRLFTDVII CVEGKEFPCH RAVLSACSSY FRAMFCNDHR ESREMLVEIN GILAEAMECF
LQYVYTGKVK ITTENVQYLF ETSSLFQISV LRDACAKFLE EQLDPCNCLG IQRFADTHSL
KTLFTKCKNF ALQTFEDVSQ HEEFLELDKD ELIDYICSDE LVIGKEEMVF EAVMRWVYRA
VDLRRPLLHE LLTHVRLPLL HPNYFVQTVE VDQLIQNSPE CYQLLHEARR YHILGNEMMS
PRTRPRRSTG YSEVIVVVGG CERVGGFNLP YTECYDPVTG EWKSLAKLPE FTKSEYAVCA
LRNDILVSVI GGRINGRDVW IYNSQLNIWI RVASLNKGRW RHKMAVLLGK VYVVGGYDGQ
NRLSSVECYD SFSNRWTEVA PLKEAVSSPA VTSCVGKLFV IGGGPDDNTC SDKVQSYDPE
TNSWLLRAAI PIAKRCITAV SLNNLIYVAG GLTKAIYCYD PVEDYWMHVQ NTFSRQENCG
MSVCNGKIYI LGGRRENGEA TDTILCYDPA TSIITGVAAM PRPVSYHGCV TIHRYNEKCF
KL
//
