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Database: UniProt
Entry: W5TRI4_9NOCA
LinkDB: W5TRI4_9NOCA
Original site: W5TRI4_9NOCA 
ID   W5TRI4_9NOCA            Unreviewed;       307 AA.
AC   W5TRI4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 52.
DE   SubName: Full=Putative RNA polymerase sigma factor {ECO:0000313|EMBL:AHH21774.1};
GN   ORFNames=NONO_c70130 {ECO:0000313|EMBL:AHH21774.1};
OS   Nocardia nova SH22a.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=1415166 {ECO:0000313|EMBL:AHH21774.1, ECO:0000313|Proteomes:UP000019150};
RN   [1] {ECO:0000313|EMBL:AHH21774.1, ECO:0000313|Proteomes:UP000019150}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SH22a {ECO:0000313|EMBL:AHH21774.1};
RX   PubMed=24747905;
RA   Luo Q., Hiessl S., Poehlein A., Daniel R., Steinbuchel A.;
RT   "Insights into the Microbial Degradation of Rubber and Gutta-Percha by
RT   Analysis of the Complete Genome of Nocardia nova SH22a.";
RL   Appl. Environ. Microbiol. 80:3895-3907(2014).
CC   -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC       formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC       omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC       transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
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DR   EMBL; CP006850; AHH21774.1; -; Genomic_DNA.
DR   RefSeq; WP_025353062.1; NZ_CP006850.1.
DR   AlphaFoldDB; W5TRI4; -.
DR   STRING; 1415166.NONO_c70130; -.
DR   KEGG; nno:NONO_c70130; -.
DR   PATRIC; fig|1415166.3.peg.7199; -.
DR   eggNOG; COG1595; Bacteria.
DR   HOGENOM; CLU_047691_22_0_11; -.
DR   OrthoDB; 3211555at2; -.
DR   Proteomes; UP000019150; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 3.10.450.50; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR037401; SnoaL-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR30173:SF36; ECF-FAMILY RNA POLYMERASE SIGMA FACTOR-RELATED; 1.
DR   PANTHER; PTHR30173; SIGMA 19 FACTOR; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   Pfam; PF12680; SnoaL_2; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019150};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          13..73
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          113..159
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
FT   DOMAIN          180..278
FT                   /note="SnoaL-like"
FT                   /evidence="ECO:0000259|Pfam:PF12680"
SQ   SEQUENCE   307 AA;  33681 MW;  EE4B4F5717446A5D CRC64;
     MTAADQHTER FVHLRPLLFT IAYEILGSAT EADDVLQDSY LRWVRVDPAV VRDTKSYLAQ
     LVTRQALNTL RAGASRREEY VGPWLPEPLL LADGDASADV VLAESVSMGM LVVLETLTPH
     ERAVFVLRDV FGFDYDEIAS AVGRSVAAVH QMAHRAREHV RARRKRYGPV DTARTAEVTE
     RFMAAATTGD LEGLLSILAP DITWTTDSGG KVNALPELIM VGAEPVGAIL MGVFRYARRR
     PEVRIEAVNC NGQSALACYI GDSLEAVLVF EIADGRIANG YGIRNPDKLA ALEIQRTISR
     GETPPRP
//
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