ID W5U7Z5_ICTPU Unreviewed; 402 AA.
AC W5U7Z5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Methylmalonic aciduria type A protein, mitochondrial {ECO:0000313|EMBL:AHH38116.1, ECO:0000313|RefSeq:XP_017318251.1};
GN Name=MMAA {ECO:0000313|EMBL:AHH38116.1};
GN Synonyms=mmaa {ECO:0000313|RefSeq:XP_017318251.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH38116.1};
RN [1] {ECO:0000313|EMBL:AHH38116.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH38116.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017318251.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017318251.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB
CC subfamily. {ECO:0000256|ARBA:ARBA00009625}.
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DR EMBL; JT407772; AHH38116.1; -; mRNA.
DR RefSeq; XP_017318251.1; XM_017462762.3.
DR STRING; 7998.ENSIPUP00000006727; -.
DR Ensembl; ENSIPUT00000007021; ENSIPUP00000006727; ENSIPUG00000004655.
DR GeneID; 108262120; -.
DR KEGG; ipu:108262120; -.
DR CTD; 166785; -.
DR OMA; WMWERID; -.
DR OrthoDB; 159517at2759; -.
DR Proteomes; UP000221080; Chromosome 3.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd03114; MMAA-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005129; GTPase_ArgK.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00750; lao; 1.
DR PANTHER; PTHR23408:SF3; METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL; 1.
DR PANTHER; PTHR23408; METHYLMALONYL-COA MUTASE; 1.
DR Pfam; PF03308; MeaB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
SQ SEQUENCE 402 AA; 44112 MW; 7832B9B34ED189E7 CRC64;
MAPTALLPFL YRTRTLSSAA ARHSSQILRR TSAELHHGPV CVLSHRRNVS TEEALSHSVS
DLTVRERTVL ERLYDGLVRG QRSSLAECIT LVETQHPRKK ELAQVLLQRV LAYRQERERI
AGGKPVAFRV GLSGPPGAGK SSFIEVLGKM LTGKGHNVSV LAVDPSSCTT GGSLMGDKTR
MTELSRDMNA FIRPSPSSGT LGGVTRTTNE AIVLCEGAGY DIVLVETVGV GQSEFAVADM
VDLFVLLIPP AGGDELQGIK RGIIEKADLV VVTKSDGDLV VPARRIQAEY TSALKLLRKK
SKTWTPKVVR VSSQTGQGVP ELWDIMLQYR DAVLSSGELQ TRRREQQKVW LWSLIQENAL
RHFQEHPEVR AALPEMERRV AQGDVSPGLA ADLLLRAFRT TQ
//
