ID W5UEN1_ICTPU Unreviewed; 414 AA.
AC W5UEN1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Abhydrolase domain-containing protein 3 {ECO:0000313|EMBL:AHH40408.1};
DE SubName: Full=Phospholipase ABHD3 isoform X4 {ECO:0000313|RefSeq:XP_017328115.1};
GN Name=ABHD3 {ECO:0000313|EMBL:AHH40408.1};
GN Synonyms=abhd3 {ECO:0000313|RefSeq:XP_017328115.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH40408.1};
RN [1] {ECO:0000313|EMBL:AHH40408.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH40408.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017328115.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017328115.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC family. {ECO:0000256|ARBA:ARBA00010884}.
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DR EMBL; JT413863; AHH40408.1; -; mRNA.
DR RefSeq; XP_017328115.1; XM_017472626.3.
DR Ensembl; ENSIPUT00000005369; ENSIPUP00000005144; ENSIPUG00000003540.
DR GeneID; 108268000; -.
DR CTD; 171586; -.
DR OrthoDB; 3665677at2759; -.
DR Proteomes; UP000221080; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR000952; AB_hydrolase_4_CS.
DR InterPro; IPR012020; ABHD4.
DR PANTHER; PTHR10794; ABHYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10794:SF50; PHOSPHOLIPASE ABHD3; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR PIRSF; PIRSF005211; Ab_hydro_YheT; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS01133; UPF0017; 1.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AHH40408.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 141..382
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
SQ SEQUENCE 414 AA; 46595 MW; 320F452485DC4D18 CRC64;
MMTLDLNLHV LTKELSVYLE NQVRVGGFLG SGVGLALALG FGVAYACYYW TSVAKKPKLV
SGGKKFYEFL KENCPVVTET YYPPFWCWES RVQTLLRPFL TAKPWVSYRN ELIRAPDGGQ
ISLDWFDNED SLSHPDSSTR PTVLLLPGLT GTSRESYILH MVQQSRELGY RCVVFNNRGV
SGEKLLTPRT YCAANTEDLE MVIEHVNNTY PTAPIMAAGV SMGGMMLANY LGRKGHATCL
KGVVVFSAGW DVFKCTASLE KPLDRFLFNS YLTSCLQASV HRHRPVLERN YDIDHVMKAK
TIREFDERFT SKMFGYPTND DYYRDASPIY KLKSVQVPML CLNAADDVFS PNHAIPVEAV
KQNPNLALLI TCHGGHIGFL EGFWPRHSTY MDRVFRQFIK AVVENGSALT DIAS
//
