ID W5UMU7_ICTPU Unreviewed; 1495 AA.
AC W5UMU7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Collagen alpha-1(II) chain {ECO:0000313|EMBL:AHH43065.1};
GN Name=col2a1 {ECO:0000313|EMBL:AHH43065.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH43065.1};
RN [1] {ECO:0000313|EMBL:AHH43065.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH43065.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
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DR EMBL; JT419402; AHH43065.1; -; mRNA.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 6.20.200.20; -; 1.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR000885; Fib_collagen_C.
DR InterPro; IPR001007; VWF_dom.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF58; COLLAGEN ALPHA-1(II) CHAIN; 1.
DR Pfam; PF01410; COLFI; 1.
DR Pfam; PF01391; Collagen; 3.
DR Pfam; PF00093; VWC; 1.
DR SMART; SM00038; COLFI; 1.
DR SMART; SM00214; VWC; 1.
DR SUPFAM; SSF57603; FnI-like domain; 1.
DR PROSITE; PS51461; NC1_FIB; 1.
DR PROSITE; PS01208; VWFC_1; 1.
DR PROSITE; PS50184; VWFC_2; 1.
PE 2: Evidence at transcript level;
KW Collagen {ECO:0000313|EMBL:AHH43065.1};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydroxylation {ECO:0000256|ARBA:ARBA00023278};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1495
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004874571"
FT DOMAIN 34..92
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 1264..1495
FT /note="Fibrillar collagen NC1"
FT /evidence="ECO:0000259|PROSITE:PS51461"
FT REGION 98..1251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..233
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..820
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 905..929
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1205..1220
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1495 AA; 145231 MW; ABB0B2BF47C990E8 CRC64;
MMSFVHSRIF LFLALSLAQV LFVKCQDGNS GDELSCFEDG QVYTNRDVWK PEPCRICVCD
SGTILCDDVQ CDEVINCEKV IIPDGECCPV CQSTFPDRDG GGGGDHNSRV YKGQKGEPGD
VPIITGLPGR QGPMGPPGSP GFRGDQGPKG RPGVRGPPGY DGEPGIPGQP GEPGPPGHPP
GGQLSSQMAE GFGGDKAAGQ HAMIPGQRGE AGARGPPGPN GLAGPPGPQG APGEPGDTGP
MGPAGQRGPE GPPGKPGEDG EAGTSGSTGE TGFPGSAGAR GFPGTPGPPG LKGHRGHQGP
EGLKGERGAV GSKGESGGTG PMGVPGPMGP RGMPGERGRP GPSGAPGTRG AQGNVGKPGP
MGPLGLSGSA GYPGAPGMKG QPGPTGVRGP EGPQGPRGES GPQGRPGPIG LQGPMGTDGG
PGTKGPVGTV GPQGPIGLPG PHGPPGPQGS TGQPGIKGQL GDVGVPGFKG EAGPKGEQGP
PGAQGSIGPQ GEEGKRGLRG DPGSVGPPGP VGERGAPGNR GFPGQDGLQG AKGAVGERGI
SGVSGPKGST GDPGRTGEPG LPGARGLTGT PGVQGAEGKP GPLGPTGEDG RPGPPGSIGT
KGPEGSMGLP GPRGFSGDPG KPGEQGSPGP PGQRGLPGKE GEVGPLGPTG PPGPAGDRGE
QGPPGMHGFQ GLPGPAGPVG EGGKPGDQGI HGEGGPVGPL GPRGERGTPG ERGELGSPGL
QGPKGIPGAP GSDGPKGSPG PAGTVGDLGP PGLQGMPGER GISGPPGPKG DRGSVGEKGS
EGTSGNDGAR GLPGPLGPAG PPGPSGEKGE PGPKGPPGPH GSRAMPGSRG EPGPTGAVGF
PGPPGPDGQP GVKGEPGEPG QKGDAGSPGH QGLSGPPGPM GPVGVAGPKG GRGTQGAPGP
TGFPGSPGKV GPPGPTGSLG QPGPVGPPGK EGPSGLRGDH GPPGRQGERG QAGPAGSPGD
KGDPGEDGPT GPDGPPGPAG TTGQRGIVGL PGQRGERGML GLPGPAGPPG KAGTSGSPGD
KGPPGPVGAP GANGPRGDAG PDGPAGADGP PGKEGVIGER GDRGDSGPEG LTGPRGAPGT
PGPVGTTGGP GKRGDVGSRG PVGPPGPAGK RGLPGPQGPR GDKGELGDHG ERGQKGHRGY
TGLQGLPGSP GTTGDQGPSG IVGPSGQRGP PGPIGPPGKE GYIGQPGPMG PPGSRGISGD
IGPEGPPGEP GPPGLPGSPG PPIAAMEDMF GGPQDYDAGP PPPEFPEDEA LPKSNLTDMF
QADPGVQATL KALSSQIESM RSPDGSKKHP ARTCEDLKQC YPLKKSGEYW VDPNQGSSED
AIKVYCNMET GETCISAEPS SIPRKSWWST PGNKPVWFGA MNGGTYFTYG NKDQPANSVT
VQMTFIRLLS KEASQTITYH CKNAVGYKDE ATGNLKKAVI LKASNDLELK AEGNNRFRYT
VLEDSCSQAN SNWGKTVFEY RTQKTARLPI VDIATVDVGR PDQEFGIDIG PVCFL
//
