ID   W5W487_9PSEU            Unreviewed;       622 AA.
AC   W5W487;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Beta-N-acetylhexosaminidase {ECO:0000313|EMBL:AHH95281.1};
DE            EC=3.2.1.52 {ECO:0000313|EMBL:AHH95281.1};
GN   ORFNames=KALB_1911 {ECO:0000313|EMBL:AHH95281.1};
OS   Kutzneria albida DSM 43870.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Kutzneria.
OX   NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH95281.1, ECO:0000313|Proteomes:UP000019225};
RN   [1] {ECO:0000313|EMBL:AHH95281.1, ECO:0000313|Proteomes:UP000019225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH95281.1};
RX   PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA   Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA   Bechthold A., Kalinowski J., Luzhetskyy A.;
RT   "Complete genome sequence of producer of the glycopeptide antibiotic
RT   Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT   of Pseudonocardiaceae.";
RL   BMC Genomics 15:885-885(2014).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
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DR   EMBL; CP007155; AHH95281.1; -; Genomic_DNA.
DR   RefSeq; WP_025355465.1; NZ_CP007155.1.
DR   AlphaFoldDB; W5W487; -.
DR   STRING; 1449976.KALB_1911; -.
DR   KEGG; kal:KALB_1911; -.
DR   PATRIC; fig|1449976.3.peg.1906; -.
DR   eggNOG; COG3525; Bacteria.
DR   HOGENOM; CLU_010969_0_1_11; -.
DR   OrthoDB; 9763537at2; -.
DR   Proteomes; UP000019225; Chromosome.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06564; GH20_DspB_LnbB-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR43678:SF1; BETA-N-ACETYLHEXOSAMINIDASE; 1.
DR   PANTHER; PTHR43678; PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000313|EMBL:AHH95281.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AHH95281.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019225};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..622
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038922540"
FT   DOMAIN          480..622
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   ACT_SITE        302
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   622 AA;  67357 MW;  1D5D662345CFE544 CRC64;
     MASTPARLSA AILLALTLIT PSAHAGAAPA ANTKPSTIPA LRQWTGGTGS FTFGPGSRVV
     LGSTVLSSTA NTFAADLKSL YGRDFTPVVG TPRPGDVYLA LGGADPQEGY TLSITDRITI
     TAPTDTGLFN GTRTVLQLLH QGTSVPQGSA RDWPSYPQRG LMVDDGRKFF TLDWLIDQVR
     ELAYLKMNYL HLHLSDNEGF RVESTSHPEV VSTEHLSKAE VRTLLAVAAA YHVTVVPEID
     MPGHLRAVLN AHPDLRLTGA DGSVSTDFID LSKDGSYALL KDLITEYAEL FPGPYFHIGA
     DEYVGNYGNY PQVLAYAKQH YGANAVAKDT YLGFVNWADD LVRASGKTTR AWNDGLYGGS
     AVTVHPDVLV EFWYNYGLSP QQLVDGGHQI MNSSYTPTYY VLGRGKASPA TTYEQWTPNL
     FQGNQSLTDP SHNLGEKVHV WCDFPDAETE AHVASGIRDL LRVVAQQTWG SAKPADGYSA
     FQDVIGLIGR NPAWPVGNLA ANRPITVSST ETPDFPGYNA VDGDYATRWS SAYGDGEWIT
     VDLGSVHAVS RVKLSWETAY GKAYQVQTSV DGTNWNTIYS TNAGRGGTED LTGLTGSGRY
     VRMQGVTRAT GWGYSLYEFE VY
//