ID   W5W7G6_9PSEU            Unreviewed;       726 AA.
AC   W5W7G6;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Peptidase S53 domain-containing protein {ECO:0000259|PROSITE:PS51695};
GN   ORFNames=KALB_3739 {ECO:0000313|EMBL:AHH97103.1};
OS   Kutzneria albida DSM 43870.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Kutzneria.
OX   NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH97103.1, ECO:0000313|Proteomes:UP000019225};
RN   [1] {ECO:0000313|EMBL:AHH97103.1, ECO:0000313|Proteomes:UP000019225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH97103.1};
RX   PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA   Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA   Bechthold A., Kalinowski J., Luzhetskyy A.;
RT   "Complete genome sequence of producer of the glycopeptide antibiotic
RT   Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT   of Pseudonocardiaceae.";
RL   BMC Genomics 15:885-885(2014).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR   EMBL; CP007155; AHH97103.1; -; Genomic_DNA.
DR   AlphaFoldDB; W5W7G6; -.
DR   STRING; 1449976.KALB_3739; -.
DR   KEGG; kal:KALB_3739; -.
DR   PATRIC; fig|1449976.3.peg.3766; -.
DR   eggNOG; COG1554; Bacteria.
DR   eggNOG; COG4934; Bacteria.
DR   HOGENOM; CLU_012501_0_0_11; -.
DR   OrthoDB; 3480681at2; -.
DR   Proteomes; UP000019225; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd04056; Peptidases_S53; 1.
DR   CDD; cd11377; Pro-peptidase_S53; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR006644; Cadg.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015366; S53_propep.
DR   InterPro; IPR030400; Sedolisin_dom.
DR   PANTHER; PTHR14218:SF42; PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR14218; PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2; 1.
DR   Pfam; PF05345; He_PIG; 2.
DR   Pfam; PF09286; Pro-kuma_activ; 1.
DR   SMART; SM00736; CADG; 1.
DR   SMART; SM00944; Pro-kuma_activ; 1.
DR   SUPFAM; SSF49313; Cadherin-like; 2.
DR   SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51695; SEDOLISIN; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019225};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..726
FT                   /note="Peptidase S53 domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038410517"
FT   DOMAIN          204..547
FT                   /note="Peptidase S53"
FT                   /evidence="ECO:0000259|PROSITE:PS51695"
FT   REGION          361..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   726 AA;  74275 MW;  27D34F4019D08F90 CRC64;
     MRREVRAIAL AIAPLPIVAA VALGGVAQAA QAQVAVPGNV NPAVATSHRA GDLPADRQLS
     VAVGLKLHNT AELDGFLAQV SNPRSAMYGH YLTPQQFADR FGPTKAELDR VSSFLTGKGL
     HVTGTNNQVV NATGSAEQVS AAFGTRLGVY QDPAANRQFF ANDSAPLLPS GVAELVQGVS
     GLDNHAVRKH SEVAAPSANP NASGLAPDAL RSIYNTNPIG GDGSGQTVVL YEFDGYKQSD
     IAYYDKNYNL GSSAPVTVPV NGQNYDSNPG AGQDEVTLDI ELVQAMAPKA STLVYEAENS
     DPGELNMVNQ IVKDNKASIT SISWGLCEKD MATSQMTNVN NAYKQGEAQG QSFFAATGDD
     GSRGCTRSNS GSSVVSAGWP GTSPSVTGVG GTTLTVGSNN TYGSERGWSG SGGGTSTVFD
     APSWQTGVNG KRTEPDVALD ADPQTGYAIY TQGSWKQYGG TSCAAPMWAG WAALYNQKAG
     KKLGNGNQAF YQIGAGADYG KAFHDITSGS NTDFSAKAGY DQVTGWGSYN GSGLFTVLNG
     TPTGNTVSVT NPGDQTTKVG GSVNLQIKAT DSSSSAKLTY SASGLPAGLS IDSASGLITG
     TASTAGTSNV TVTVTDDTKA SGNTSFKWTV GDTPPPTGTV TVTSPGDQWG FKGYKLFQNI
     QVKATASDGG ALTFSATGLP AGVTISSSGL ISGTPTTAGT TTVTVTAKEA NGTSGSASFK
     FQIYGF
//