ID W5W7P8_9PSEU Unreviewed; 832 AA.
AC W5W7P8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:AHH94239.1};
GN ORFNames=KALB_865 {ECO:0000313|EMBL:AHH94239.1};
OS Kutzneria albida DSM 43870.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Kutzneria.
OX NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH94239.1, ECO:0000313|Proteomes:UP000019225};
RN [1] {ECO:0000313|EMBL:AHH94239.1, ECO:0000313|Proteomes:UP000019225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH94239.1};
RX PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA Bechthold A., Kalinowski J., Luzhetskyy A.;
RT "Complete genome sequence of producer of the glycopeptide antibiotic
RT Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT of Pseudonocardiaceae.";
RL BMC Genomics 15:885-885(2014).
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DR EMBL; CP007155; AHH94239.1; -; Genomic_DNA.
DR RefSeq; WP_025354496.1; NZ_CP007155.1.
DR AlphaFoldDB; W5W7P8; -.
DR STRING; 1449976.KALB_865; -.
DR KEGG; kal:KALB_865; -.
DR PATRIC; fig|1449976.3.peg.869; -.
DR eggNOG; COG0639; Bacteria.
DR eggNOG; COG4639; Bacteria.
DR HOGENOM; CLU_016728_0_0_11; -.
DR OrthoDB; 9807890at2; -.
DR Proteomes; UP000019225; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd07423; MPP_Prp_like; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041780; MPP_PrpE-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR024028; PNKP_bac.
DR InterPro; IPR032380; PNKP_ligase_dom.
DR NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR PANTHER; PTHR42850:SF7; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE PRPE [ASYMMETRICAL]; 1.
DR PANTHER; PTHR42850; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16542; PNKP_ligase; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000019225}.
FT DOMAIN 182..377
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 465..827
FT /note="Polynucleotide kinase-phosphatase ligase"
FT /evidence="ECO:0000259|Pfam:PF16542"
SQ SEQUENCE 832 AA; 91444 MW; 54A7B923CE5C1ACB CRC64;
MSRLGIPQLA LVALVGVSGS GKSTFAARHF RATEVISSDH CRGLVSDDPN DQSATKDAFD
VLHYIAGKRL AAGRLTVVDA TNVQREGRAQ LVALAREHDV LPVAIVLDMP EGLCLRRNAE
RPDRDFGAHV LRRQRADLHK SLRHLEKEGF RRVHVLRSPE EVAETVLVRE PLLNDRRADT
GPFDVIGDVH GCRAELEQLL AELGYLVERD AEGRPVGAAH PRGRRALFVG DLVDRGPDTP
GVLRLVMGMV AAGTAMCVCG NHEQKLVRAL RGKKVTVAHG LAESLAQLSA ESAEFRKLAE
QFCYDLVSHY VLDGGKLVVA HAGLPERFQG RASGRVRSFA LYGESTGETD EYGLPVRYPW
ANDYRGAAAV VYGHTPVLDA EWVNNTICLD TGCVFGGRLT ALRYPERELV SVAAQQVWYE
PVRPLQPVNP VRPDDELNLT DVLGKRVVET AEHGRITVRA ENAAAALEVM SRFAIEPGSL
LYLPPTMAPT ATSQRADVLE HPEEAFAGYL AAGVREVICE EKHMGSRAVL LVRRDGGAVH
TRTGRAFFDQ RLTDQVLARL QAAISAAGLW SELATDWLLL DAELLPWSAK AEPLIREQYA
AVGAAASAAL PAALDMLRAA ADRGVDVTDL LQRNESRANN ADAFRAAYRR YCWPTDGLRG
MRVAPFQVLA SEGRTYHDRP HSWHLDLLNR LSTADPEFVA TTDNLLVDTG NPDSVAAGVR
WWSELTEDGG EGMVVKPMAN LVRGKRGVVQ PGVKVRGREY LRIIYGPDYT EPANLDRLRK
RNLGTKRSLA LREYMLGIEG LRRLTSGEPL WRVHECVFAV LALESEPVDP RL
//
