ID W5WF48_9PSEU Unreviewed; 345 AA.
AC W5WF48;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=VOC domain-containing protein {ECO:0000259|PROSITE:PS51819};
GN ORFNames=KALB_6025 {ECO:0000313|EMBL:AHH99385.1};
OS Kutzneria albida DSM 43870.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Kutzneria.
OX NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH99385.1, ECO:0000313|Proteomes:UP000019225};
RN [1] {ECO:0000313|EMBL:AHH99385.1, ECO:0000313|Proteomes:UP000019225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH99385.1};
RX PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA Bechthold A., Kalinowski J., Luzhetskyy A.;
RT "Complete genome sequence of producer of the glycopeptide antibiotic
RT Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT of Pseudonocardiaceae.";
RL BMC Genomics 15:885-885(2014).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954,
CC ECO:0000256|RuleBase:RU000683};
CC -!- SIMILARITY: Belongs to the extradiol ring-cleavage dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00008784, ECO:0000256|RuleBase:RU000683}.
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DR EMBL; CP007155; AHH99385.1; -; Genomic_DNA.
DR AlphaFoldDB; W5WF48; -.
DR STRING; 1449976.KALB_6025; -.
DR KEGG; kal:KALB_6025; -.
DR PATRIC; fig|1449976.3.peg.6047; -.
DR eggNOG; COG0346; Bacteria.
DR HOGENOM; CLU_052361_3_0_11; -.
DR OrthoDB; 317332at2; -.
DR Proteomes; UP000019225; Chromosome.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR CDD; cd07256; HPCD_C_class_II; 1.
DR Gene3D; 3.10.180.10; 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1; 2.
DR Gene3D; 4.10.1270.10; homoprotocatechuate 2,3-dioxygenase domains; 1.
DR InterPro; IPR011981; DHPA_dOase_Mn/Fe.
DR InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR InterPro; IPR044904; HPCD_C_sf.
DR InterPro; IPR037523; VOC.
DR InterPro; IPR000486; Xdiol_ring_cleave_dOase_1/2.
DR NCBIfam; TIGR02295; HpaD; 1.
DR PANTHER; PTHR21366:SF27; BLL2967 PROTEIN; 1.
DR PANTHER; PTHR21366; GLYOXALASE FAMILY PROTEIN; 1.
DR Pfam; PF00903; Glyoxalase; 2.
DR SUPFAM; SSF54593; Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase; 1.
DR PROSITE; PS00082; EXTRADIOL_DIOXYGENAS; 1.
DR PROSITE; PS51819; VOC; 2.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797,
KW ECO:0000256|RuleBase:RU000683};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964, ECO:0000256|RuleBase:RU000683};
KW Iron {ECO:0000256|RuleBase:RU000683};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000683};
KW Reference proteome {ECO:0000313|Proteomes:UP000019225}.
FT DOMAIN 9..123
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
FT DOMAIN 144..263
FT /note="VOC"
FT /evidence="ECO:0000259|PROSITE:PS51819"
SQ SEQUENCE 345 AA; 39032 MW; D205588004B18EC0 CRC64;
MSTAPDVIRC AYAEFVVSDL RASRAFYVDV LGLVVTHEDA DTIHLRAFEE YLHHSLVLRR
GPVPALAVLG YRVRTPADLD LAEAYYRELG VRVRRREPGA TLGIGEAVRV EDPLGFPIEF
FHEAVHVERF TQRYDTHGAG AISRLDHFNL NTPDVPAARK YYEGLGFRVS EDIQDSDGTV
YAAWMFRKPT VHDVALTGGD GPRLHHIAFA THERHQILHI CDHLGALRQS DMIERGPGRH
GVSNAFYLYL RDPDGHRIEI YTHDYYTGDP DNPVITWDVH DNQRRDWWGN AVVPSWYTEA
SPVLDLDGAP RPLVARTDAR EMDVTIGADG FSYTRSTEFK LGEQV
//
