ID   W5WH12_9PSEU            Unreviewed;       930 AA.
AC   W5WH12;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN   ORFNames=KALB_4095 {ECO:0000313|EMBL:AHH97459.1};
OS   Kutzneria albida DSM 43870.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Kutzneria.
OX   NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH97459.1, ECO:0000313|Proteomes:UP000019225};
RN   [1] {ECO:0000313|EMBL:AHH97459.1, ECO:0000313|Proteomes:UP000019225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH97459.1};
RX   PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA   Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA   Bechthold A., Kalinowski J., Luzhetskyy A.;
RT   "Complete genome sequence of producer of the glycopeptide antibiotic
RT   Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT   of Pseudonocardiaceae.";
RL   BMC Genomics 15:885-885(2014).
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DR   EMBL; CP007155; AHH97459.1; -; Genomic_DNA.
DR   RefSeq; WP_025357540.1; NZ_CP007155.1.
DR   AlphaFoldDB; W5WH12; -.
DR   STRING; 1449976.KALB_4095; -.
DR   KEGG; kal:KALB_4095; -.
DR   PATRIC; fig|1449976.3.peg.4127; -.
DR   eggNOG; COG0470; Bacteria.
DR   eggNOG; COG2197; Bacteria.
DR   HOGENOM; CLU_006850_4_1_11; -.
DR   OrthoDB; 3656034at2; -.
DR   Proteomes; UP000019225; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019225}.
FT   DOMAIN          859..924
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   930 AA;  99478 MW;  0FDD949DD506D86C CRC64;
     MDEHTGDLGA VPRPEPDPGE PIVGRDAELA RLVRAMDSAS ADPAAVLVGD MGTGKSALLD
     RAVRHAEAGG ARVLRAEGSE LESSLAFSAL HQLLRPVLSE VDRLPDRQRA AILDAFGTGP
     AMPRYSSAPD LMLIGVAVLS LLSALGDQRP VLVVLDDAQW FDRASLDALS FAARRLEGEP
     VTMLIGARGG DHLPGFDRHV PTLILGPLDN AAANQLLDLQ PKSPTGHTRT RILDQAGGNP
     LALVELTRTA TAADAATGLP TAGPLPLSDH LERIFAARLN GLPAATARAL LLLAAMDSVD
     FTIAASAGLP NAEDDAWLPA EQARLIRRTG RDVRFRHPLV RSAVYHAASL GARREAHLAL
     AAMLRDEPDR RAWHLAAACP RPDAAVSAEL ERTAARARRR GGHAAAAKAL QRAAELAPQR
     ENSARLLVEA AAAAVFTGDI AWVKELAAAV RARTDDAKLL AAAAVQAGRL AVLTVRHSVV
     FSRLADTAEE LAARQPAAGL ELLAHAAVVR FYSGADTQRH RIQDILRSLT EDASYTGLRT
     WVRAVCDPFG DRSELVSLLP QLAAEAQARP EQLTTVGIMA WLLDETPQAV RAFDEAFASW
     ELQGTLPEGL GGAVAWAYVE RGRWEQAREA CARTIAVGRS VGLDHAVACA ATVDAAVLAY
     QGDATAARAE EALALIDPLE SRSVCVYARR ALGAAAAAEG AYETAYDQLR MVFTADGAPL
     HYHASYPAVA DLAAAAVRCG RREEAAAIVE RCARALAESA SPRLRALINR ARGLLADPED
     AEPHFRASLA DPVLAHWPFE RAQILLDLAE WLRRRRRIAE ARTPLTEALE TFRRLGAHPW
     IERARAESRA AGLDVTDTAP DALAALSPQQ QQIIRLAARG LTNREIGERL FLSPRTVSSH
     LYRSFPKLGI TARSQLRDLI EDTLATAGHS
//