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Database: UniProt
Entry: W5WUT3_BDEBC
LinkDB: W5WUT3_BDEBC
Original site: W5WUT3_BDEBC 
ID   W5WUT3_BDEBC            Unreviewed;       478 AA.
AC   W5WUT3;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   25-OCT-2017, entry version 31.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=BDW_00005 {ECO:0000313|EMBL:AHI04511.1};
OS   Bdellovibrio bacteriovorus W.
OC   Bacteria; Proteobacteria; Oligoflexia; Bdellovibrionales;
OC   Bdellovibrionaceae; Bdellovibrio.
OX   NCBI_TaxID=765869 {ECO:0000313|EMBL:AHI04511.1, ECO:0000313|Proteomes:UP000019233};
RN   [1] {ECO:0000313|EMBL:AHI04511.1, ECO:0000313|Proteomes:UP000019233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W {ECO:0000313|EMBL:AHI04511.1,
RC   ECO:0000313|Proteomes:UP000019233};
RA   Mussa H.J., Iandolo J.J.;
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP002190; AHI04511.1; -; Genomic_DNA.
DR   EnsemblBacteria; AHI04511; AHI04511; BDW_00005.
DR   KEGG; bbw:BDW_00005; -.
DR   PATRIC; fig|765869.4.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000019233; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019233};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019233}.
FT   DOMAIN      172    301       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      382    451       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   478 AA;  54523 MW;  BF9FF9841BC0D890 CRC64;
     MKGSMLELNS SFWSHIKTKM KSRNDNNKLL DTWLDPIEYV DTQGTLERPK LILGVPNALH
     QYFVIENLQE KIYAEISDSY GKPFEVEFSI TGHKVNTHIE TSTQPEETSS ADILQAQLAR
     SQGLQMGGQP TRPGGPDALN SESTFSTFVV GKNSEFAHAA CFNVARNPGA DDYNPLYIYG
     PVGMGKTHLL HAAGNHIKEH FQNLRITYIS AERFMNECIS SIRRYEMDKF RQKYRENSDI
     LLVDDVQFIA RGEAVQEEFF HTINSFIDSR KQVILASDRM PKDIHGLEDR SRTRLERGLI
     ADITMPDLET RIAILRYKAE KFNVRIPEDV ATYIARISKR SIRELEGNLK KVKMFSELQG
     LPIDYELVKR ILSHHETQSS ISAEEIMKMV ADHFKVRVLD LKSSSRAKPI VIPRQIAMYL
     IKKFLDRSLV DIGKVFGGKD HTTVINALER VRNLQAADQD IAKDIEDLET RIHNITGV
//
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