ID W6ASY6_9CAUD Unreviewed; 253 AA.
AC W6ASY6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=SHOU24_45 {ECO:0000313|EMBL:AHI61242.1};
OS Vibrio phage SHOU24.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes.
OX NCBI_TaxID=1414739 {ECO:0000313|EMBL:AHI61242.1, ECO:0000313|Proteomes:UP000019307};
RN [1] {ECO:0000313|EMBL:AHI61242.1, ECO:0000313|Proteomes:UP000019307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=25115946; DOI=10.1007/s00705-014-2160-x;
RA Yuan L., Cui Z., Wang Y., Guo X., Zhao Y.;
RT "Complete genome sequence of virulent bacteriophage SHOU24, which infects
RT foodborne pathogenic Vibrio parahaemolyticus.";
RL Arch. Virol. 159:3089-3093(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; KF623293; AHI61242.1; -; Genomic_DNA.
DR RefSeq; YP_009006446.1; NC_023569.1.
DR GeneID; 18503143; -.
DR KEGG; vg:18503143; -.
DR OrthoDB; 8399at10239; -.
DR Proteomes; UP000019307; Genome.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR012327; MeTrfase_D12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR30481; DNA ADENINE METHYLASE; 1.
DR PANTHER; PTHR30481:SF3; DNA ADENINE METHYLASE; 1.
DR Pfam; PF02086; MethyltransfD12; 1.
DR PRINTS; PR00505; D12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AHI61242.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019307};
KW Transferase {ECO:0000313|EMBL:AHI61242.1}.
SQ SEQUENCE 253 AA; 28631 MW; 17A95A0652BB6451 CRC64;
MKYMGSKARI AKDILPIILE GRKPGQYYVE PFGGGANSIC EVDNPRIYND VNDLIVACLK
EVSNGWIPPV DIDRDFYSEC RDKFKTGIYS EEEEHVIGYV GINGSYGGRW FDGGYAGITT
TREGKIRNYP EEAWRNVMAQ APKLAGVEFH SGCYLTLEIP AKSIIYCDPP YKGTKEYKFA
VNSGFNSDEF WQWCRDMTKV GHSVFVSEYE APEDFVCVWE KGLSSSLRAN GVIKGDKKSL
ERLFIYQPKG VEE
//
