ID W6FG02_PANTA Unreviewed; 215 AA.
AC W6FG02;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE SubName: Full=Integrin alpha 6 {ECO:0000313|EMBL:AHJ25881.1};
DE Flags: Fragment;
GN Name=ITGA6 {ECO:0000313|EMBL:AHJ25881.1};
OS Panthera tigris altaica (Siberian tiger).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae;
OC Panthera.
OX NCBI_TaxID=74533 {ECO:0000313|EMBL:AHJ25881.1};
RN [1] {ECO:0000313|EMBL:AHJ25881.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ear {ECO:0000313|EMBL:AHJ25881.1};
RX PubMed=24630959; DOI=10.1016/j.gene.2014.03.023;
RA Guo Y., Liu C., Lu T., Liu D., Bai C., Li X., Ma Y., Guan W.;
RT "Generation and analysis of a large-scale expressed sequence tags from a
RT full-length enriched cDNA library of Siberian tiger (Panthera tigris
RT altaica).";
RL Gene 541:75-81(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003762}; Single-
CC pass type I membrane protein {ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|RuleBase:RU003762}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KF896585; AHJ25881.1; -; mRNA.
DR AlphaFoldDB; W6FG02; -.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR028994; Integrin_alpha_N.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF9; INTEGRIN ALPHA-6; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 3.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR PROSITE; PS51470; FG_GAP; 2.
PE 2: Evidence at transcript level;
KW Cell adhesion {ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|RuleBase:RU003762, ECO:0000313|EMBL:AHJ25881.1};
KW Receptor {ECO:0000256|RuleBase:RU003762};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT REPEAT 94..156
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 157..212
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AHJ25881.1"
FT NON_TER 215
FT /evidence="ECO:0000313|EMBL:AHJ25881.1"
SQ SEQUENCE 215 AA; 23446 MW; D0BC4040E8F70A09 CRC64;
PGTYNWKGIV RVEQKNNTFF DMNIFEDGPY EVGGETDHDE SLVPVPANSY LGFSLDSGKG
IVSKDELTFV SGAPRANHSG AVVLLKRDMK SAHLLPEHIF DGEGLASSFG YDVAVVDLNK
DGWQDIVIGA PQYFDRDGEV GGAVYVYINQ QGRWNNVKPI RLNGTKDSMF GIAVKNIGDI
NQDGYQDIAV GAPYDDLGKV FIYHGSPNGI NTKPT
//
