ID   W6FIT5_NODSP            Unreviewed;      1269 AA.
AC   W6FIT5;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=magnesium chelatase {ECO:0000256|ARBA:ARBA00012825};
DE            EC=6.6.1.1 {ECO:0000256|ARBA:ARBA00012825};
GN   ORFNames=NSP_1080 {ECO:0000313|EMBL:AHJ26465.1};
OS   Nodularia spumigena CCY9414.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Aphanizomenonaceae;
OC   Nodularia.
OX   NCBI_TaxID=313624 {ECO:0000313|EMBL:AHJ26465.1, ECO:0000313|Proteomes:UP000019325};
RN   [1] {ECO:0000313|EMBL:AHJ26465.1, ECO:0000313|Proteomes:UP000019325}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCY9414 {ECO:0000313|EMBL:AHJ26465.1};
RX   PubMed=23555932;
RA   Voss B., Bolhuis H., Fewer D.P., Kopf M., Moke F., Haas F., El-Shehawy R.,
RA   Hayes P., Bergman B., Sivonen K., Dittmann E., Scanlan D.J., Hagemann M.,
RA   Stal L.J., Hess W.R.;
RT   "Insights into the physiology and ecology of the brackish-water-adapted
RT   Cyanobacterium Nodularia spumigena CCY9414 based on a genome-transcriptome
RT   analysis.";
RL   PLoS ONE 8:E60224-E60224(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + Mg(2+) + protoporphyrin IX = ADP + 3 H(+) + Mg-
CC         protoporphyrin IX + phosphate; Xref=Rhea:RHEA:13961,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:18420,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:57306,
CC         ChEBI:CHEBI:60492, ChEBI:CHEBI:456216; EC=6.6.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001499};
CC   -!- PATHWAY: Porphyrin-containing compound metabolism.
CC       {ECO:0000256|ARBA:ARBA00023444}.
CC   -!- SIMILARITY: Belongs to the Mg-chelatase subunit H family.
CC       {ECO:0000256|ARBA:ARBA00010851}.
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DR   EMBL; CP007203; AHJ26465.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6FIT5; -.
DR   STRING; 313624.NSP_1080; -.
DR   PATRIC; fig|313624.11.peg.108; -.
DR   eggNOG; COG1429; Bacteria.
DR   HOGENOM; CLU_002017_1_2_3; -.
DR   Proteomes; UP000019325; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016851; F:magnesium chelatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   CDD; cd10150; CobN_like; 1.
DR   InterPro; IPR011771; BchH.
DR   InterPro; IPR003672; CobN/Mg_chltase.
DR   InterPro; IPR022571; Mg_chelatase_H_N.
DR   NCBIfam; TIGR02025; BchH; 1.
DR   PANTHER; PTHR44119; MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR44119:SF1; MAGNESIUM-CHELATASE SUBUNIT CHLH, CHLOROPLASTIC; 1.
DR   Pfam; PF02514; CobN-Mg_chel; 1.
DR   Pfam; PF11965; DUF3479; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Chlorophyll biosynthesis {ECO:0000256|ARBA:ARBA00023171};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:AHJ26465.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Photosynthesis {ECO:0000256|ARBA:ARBA00022531}.
FT   DOMAIN          3..127
FT                   /note="Magnesium chelatase subunit H N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11965"
SQ   SEQUENCE   1269 AA;  141836 MW;  F418A697FB5E0375 CRC64;
     MIEELRDPEN YEEFKREMET ANIFIASLIF IEDLAQKVVT AVEPHRHHLD VSVVFPSMPE
     VMRLNKMGTF SLAQLGQSKS AIAQFMRKRK EKSGAGFQDG MLKLLRTLPQ VLKFLPMEKA
     QDARNFMLSF QYWLGGSPEN LENFLLMLAD KYVLKDVDKK NFPSPTYEAP VVYPDMGIWH
     PLATTMFEDI REYLNWYTAR KDISSDLKDP LAPCVGLVLQ RTHLVTGDDA HYVAIVQELE
     SLGARVIPVF AGGLDFSKPV DAYFYEPTTN TTLIDAVISL TGFALVGGPA RQDHPKAIES
     LKRLNRPYMV ALPLVFQTTE EWMDSDLGLH PIQVALQIAI PELDGAIEPI ILSGRDGATG
     KAHALQDRVE AIAQRALKWA NLRRKPKLDK KVAITVFSFP PDKGNVGTAA YLDVFGSIFE
     VLKGLRNNGY DVQDVPETAQ ALMEQVIHDA QAQYSSPELN IAYKMSVPEY EALTPYSQRL
     EENWGPPPGN LNSDGQNLLI YGKQFGNVFI GVQPTFGYEG DPMRLLFSRS ASPHHGFAAY
     YTYLEQIWGA DAVLHFGTHG SLEFMPGKQM GMSGDCYPDN LIGSIPNLYY YAANNPSEAT
     IAKRRSYAET ISYLTPPAEN AGLYKGLKEL SELIASYQTL KDSGRGIPIV NTIMDKCRIV
     NLDKDINLPD TDAKEMTADE RDHIVGSVYR KLMEIESRLL PCGLHVIGKP PSAEEAVATL
     VNIGSLDRQE EEILSLPRII ASSIGRDIDD IYKNSDLGNL EDVQLLQDIT LATREAVAAL
     VKAQTDAEGR VSLVSRLNFF NMGKKEPWVE ALHKAGYPKV DPEALKPVFE YLEFCLKQVC
     ADNELGALLQ GLEGEYVLPG PGGDPIRNPD VLPTGKNIHA LDPQSIPTAA AVQSAKIVVD
     RLLERNKAEN EGKWPETIAC VLWGTDNIKT YGESLAQIMW MIGVRPVPDA LGRVNKLELI
     PLEELGRPRI DVVINCSGVF RDLFINQMNL LDQGVKMAAE ADEPLEMNFV RQHALKQAEE
     MGINLRQAAT RVFSNASGSY SSNINLAVEN STWDSEAELQ EMYLRRKSFS FNSDNPGVMD
     ESRQMFETSL KTADATFQNL DSSEISLTDV SHYFDSDPTK LVASLRKDGK TPASYIADTT
     TANAQVRSLT ETVRLDARTK LLNPKWYEGM LSHGYEGVRE LSKRLVNTTG WSATAGAVDN
     WIYEDTNETF IKDEEMQKRL MNLNPHSFRK IVSTLLEMNG RGYWETSDDN LDRLRELYQE
     VEDRIEGIE
//