ID W6JHE4_9MYRI Unreviewed; 1648 AA.
AC W6JHE4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
DE Flags: Fragment;
GN Name=RPB1 {ECO:0000313|EMBL:BAO48663.1};
OS Pauropodidae sp. My085.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Pauropoda;
OC Tetramerocerata; Pauropodidae.
OX NCBI_TaxID=1366095 {ECO:0000313|EMBL:BAO48663.1};
RN [1] {ECO:0000313|EMBL:BAO48663.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=My085 {ECO:0000313|EMBL:BAO48663.1};
RX PubMed=24535281; DOI=10.1038/srep04127;
RA Miyazawa H., Ueda C., Yahata K., Su Z.-H.;
RT "Molecular phylogeny of Myriapoda provides insights into evolutionary
RT patterns of the mode in post-embryonic development.";
RL Sci. Rep. 4:4127-4127(2014).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|ARBA:ARBA00006460, ECO:0000256|RuleBase:RU004279}.
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DR EMBL; AB831746; BAO48663.1; -; mRNA.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0031981; C:nuclear lumen; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd02584; RNAP_II_Rpb1_C; 1.
DR CDD; cd02733; RNAP_II_RPB1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.1360.140; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 2.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR000684; RNA_pol_II_repeat_euk.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR007073; RNA_pol_Rpb1_7.
DR InterPro; IPR038593; RNA_pol_Rpb1_7_sf.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR Pfam; PF05001; RNA_pol_Rpb1_R; 16.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
DR PROSITE; PS00115; RNA_POL_II_REPEAT; 12.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 164..467
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 1466..1648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1473..1490
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1498..1648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAO48663.1"
FT NON_TER 1648
FT /evidence="ECO:0000313|EMBL:BAO48663.1"
SQ SEQUENCE 1648 AA; 182549 MW; B915B8E56460BDF4 CRC64;
ECPGHFGHID LAKPVLHIGF LTKTIKVLRC VCFFCSKMLI NPNNPKIKDV VLKSKGMPRR
RLAHVYDLCK TRKICEGGDD DTKENEDGQE QDVFKKLGHG GCGRFQPTIR RSGLDLTAEW
KHVNDDTQEK KIPVTGERVY EIFRHISDEE CTVLGMDPKY ARPESMIVTV VPVPPLAVRP
AIVMNGSNHC QDDITHKLAD IIKCNNELIR NEQSGAAAHI IAENMKMLQF HVATLTDNDS
PGLPKAMQKS GRPLKSIKAR LKGKEGRIRG NLMGKRVDFS ARTVITPDPN LLIHQVGVPR
SIAQNMTFPE IVTPFNIDKM RDLVRRGNSQ YPGAKYIIRD NGERIDLRFH PKPSDLHLQM
GYKVERHIRD GDVVIFNRQP TLHKMSMMGH KIRVLPWSTF RLNLSVTTPY NADFDGDEMN
LHVPQSMETR AEIEELALVP RQIITPQSNQ PVMGIVQDTL CAVRKMTKRD VFLEKDQMMN
LLMYLPTWDG KMPQPAILKP KPLWTGKQLF SLIIPGNVNV IRTHSTHPDE EDDGPYKWIS
PGDTKVLVEH GTLICGIICK KTIGTSGGSL LHIVMLEMGW ETAGLFYSHN WLLLDGHSIG
INDTIADQET YIEIQDTIKK AKIDVVEVIE RAHNDELEPT PGNTLRQTFE NQVNRILNDA
RDKTGSSAQK SLSEFNNFKS MVVSGSKGSK INISQVIACV GQQNVEGKRI PFGFRKRTLP
HFIKDDYGPE SRGFVENSYL AGLTPSEFFF HAMGGREGLI DTAVKTAETG YIQRRLIKAM
ESVMVAYDGT IRNSAGQMVQ FRYGEDGLDA CHVEIQSLAT LKPSDRAFEQ KFKFDATNER
HLRRVFNESI VKELLGSASA VGQLESEWDQ LRKDREILRQ VFPKGENKIV LPCNLQRMIW
NAQKIFHINT RAPTDLSPLK VVDSVRDLSK RIIVVGGEDM LSKQANENAT LLFNCHLRST
LCTKRVAEEF KLSSEAFEWI LGEIDARFQQ SMVQPGEMVG ALAAQSLGEP ATQMTLNTFH
YAGVSAKNVT LGVPRLKEII NISKKPKTPS LTVFLVGAPA RDAEKAKDVL CRLEHTTLRK
VTANTAIYYD PDPQNTVIPE DQEFVSVYYE MPDFDPSRIS PWLLRIELDR KRMTDKKLTM
EQISEKINAG FGDDLNCIFN DDNAEKLVLR IRIMNSDDGK NDDGDDQQIV DKMTDDVFLR
CIESNMLSDM TLQGIEAIAK VYMHLPSTDD KKRIVRMETG EFKSIAEWLL ETDGTSLMRV
LSERDVDPIR TYSNDICEIF SVMGIEAVRK SVEKEMNHVI SFDGSYVNYR HLALLCEIMT
AKGHLMAITR HGINRQDTGA LMRCSFEETV DVLMEAASHA ECDYMRGVSE NIMLGQLAKM
GTGSFDLLLN NEQCKFGMEI PSNLGGGVGL FFGSTSPGSG MSPQMTPWMQ GGTPAYGSVW
SPGVGSGMTP GGAGFSPAAS DASGFSPGYS PAWSPQPGSP VSPGPVSPYI PSPAGAGLSP
SYSPSSPYGL ASPSGQSPSY SASGSNYSPT SPSYSPTSPS YSPTSPSYSP TSPSYSPTSP
SYSPTSPSYS PTSPSYSPTS PSYSPTSPSY SPTSPSYSPT SPSYSPTSPS YSPTSPSYSP
TSPSYSPTSP SYSPTSPSYS PTSPSYSP
//
