ID   W6KK57_9TRYP            Unreviewed;       856 AA.
AC   W6KK57;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=GSEM1_T00005727001 {ECO:0000313|EMBL:CCW61423.1};
OS   Phytomonas sp. EM1.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Phytomonas.
OX   NCBI_TaxID=479712 {ECO:0000313|EMBL:CCW61423.1, ECO:0000313|Proteomes:UP000027080};
RN   [1] {ECO:0000313|EMBL:CCW61423.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EM1 {ECO:0000313|EMBL:CCW61423.1};
RA   Genoscope - CEA;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCW61423.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EM1 {ECO:0000313|EMBL:CCW61423.1};
RX   PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA   Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA   Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA   Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA   Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA   Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA   Wincker P., Dollet M.;
RT   "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT   Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL   PLoS Genet. 10:e1004007-e1004007(2014).
CC   -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00330}.
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DR   EMBL; HF955064; CCW61423.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6KK57; -.
DR   EnsemblProtists; CCW61423; CCW61423; GSEM1_T00005727001.
DR   OrthoDB; 2786196at2759; -.
DR   Proteomes; UP000027080; Unassembled WGS sequence.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR   InterPro; IPR044554; APC2-like.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000027080};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          502..701
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   856 AA;  96457 MW;  2D5457E5103C4075 CRC64;
     MDDDDAWAVV SNFFERFNDD TDVLSVWYAS NEDWVHWKIA LSVLSTPPAN AMLAQALVEK
     AFTSLQTHLE SFQTSLVDPH ATLSSISTAL QHLYFAFQCV QLRLQECCER LAVLDVSCEL
     AAAVWCFLLQ PDLLTGEEPL GKPEFMEFLT RHAETFLSKD LAKSNIKEET RENEDEECVS
     NNVHLFGRLA KLSSAPPRDM VFECLHGLML SSSREIKTLW RSILDACVQD RINSLQDVYN
     KHFIKQCIAW EEEVVEPFID MALPPVCDSH ETHKFASSSY HKELMQSSLS VEFTNKTLSV
     EKKRWCEDFR KKNFILYARN RIRNFWDIMV EYPDSIPTLQ DIRYCLHTSR DENLKDELLQ
     YVRNLLASRL HRAGISTEDI LEVLSKTISS LCVLLTRSEQ GALLFTVVSD TLEHLRRRKD
     CIPEIIKLIT QPNGNASGAI DDAQSNLQRE EEDAGLNLRD INDDDEYYGD GADYRQDDTL
     KAFDTLRVLL ATISVKSLSH EYEKALAQGL LERTIHTFDT TSEEEMLERL KCVLGQDVLL
     NCAVMLWDVQ MSKRTTHQIQ EKRLNKTSPP LGLSTNTVTD ENFSRQTTLL PDAVSVDVLS
     LTAWPSLSHC FSFGVSVAVP DQYVVHPVLQ KELDYLAANF KSVKLDQRLN WILSQGRVVL
     EVDLLDPLQG HALKTVSHIL PLFAASVVLH LRDLEAKVTV STRDGTRNSS DKGTSVPISI
     DKLASRVGVS TVEKLMPCLV NLSPSVVTIY PGSTHVAIQK FVSNASNIVF KNDDSDHKGE
     EESSGLSPLQ IKAITRMIIS KLKTSAAQSL SDIHNSVKKF VDFTVRVTDI KTIMQTLLSE
     GSVACTDGKH YTLSSK
//